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Vapendavir

DRUG5 trials

Sponsors

Biota Pharmaceuticals, Inc., Vaxart, Altesa Biosciences, Inc.

Conditions

AsthmaCOPDCOPD Exacerbation AcuteCOPD With Acute Lower Respiratory InfectionChronic Lower Respiratory DiseasesChronic Respiratory DiseaseCopdEmphysema or COPD

Phase 1

Phase 1 Study Into Pharmacokinetics and Food Effect of Vapendavir in Healthy Participants and Participants With COPD
CompletedNCT05962645
Altesa Biosciences, Inc.COPD, Healthy, Lower Respiratory Disease +2
Start: 2023-05-19End: 2024-05-02Updated: 2024-07-30
A Study to Evaluate Metabolism, Excretion, and Mass Balance of [14C]Vapendavir
CompletedNCT06834295
Altesa Biosciences, Inc.Healthy Males
Start: 2025-03-12End: 2025-03-23Updated: 2025-05-28

Phase 2

A Phase 2 Study of Vapendavir in Asthmatic Adults With Symptomatic Human Rhinovirus Infection
CompletedNCT02367313
Biota Pharmaceuticals, Inc.Asthma
Start: 2015-02-28End: 2016-12-31Updated: 2018-06-01
A Study of Vapendavir Treatment of Hematopoietic Stem Cell Transplant Subjects With Symptomatic Rhinovirus Infection
WithdrawnNCT03024177
VaxartRhinovirus, Upper Respiratory Tract Infection
Updated: 2018-05-07
RCT of Vapendavir in Patients With COPD and Human Rhinovirus/Enterovirus Upper Respiratory Infection
CompletedNCT06149494
Altesa Biosciences, Inc.Chronic Lower Respiratory Diseases, Chronic Respiratory Disease, Copd +33
Start: 2023-11-20End: 2025-03-30Updated: 2025-09-30