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Vancomycin powder

DRUG5 trials

Sponsors

Vanderbilt University Medical Center, University of Tennessee, The University of Hong Kong, NYU Langone Health, Alberta Hip and Knee Clinic

Conditions

Infection of Total Hip Joint ProsthesisInfection of Total Knee Joint ProsthesisOsteoarthritisSpinal DeformitySpinal TumorSurgical Site InfectionTraumaWound Infection

Phase 1

Vancomycin Powder and Dilute Povidone Iodine Lavage for Infection Prophylaxis in High Risk Total Joint Arthroplasty
CompletedNCT04075526
NYU Langone HealthOsteoarthritis
Start: 2019-10-01End: 2025-12-13Updated: 2026-02-17

Phase 2

Topical Vancomycin for Infection Prophylaxis in TJA
Not yet recruitingNCT04993027
Alberta Hip and Knee ClinicInfection of Total Hip Joint Prosthesis, Infection of Total Knee Joint Prosthesis
Start: 2025-12-30End: 2028-12-30Target: 100Updated: 2024-07-31

Phase 4

Vancomycin in Spine Surgery
NCT01977989
University of TennesseeWound Infection
Start: 2013-10-31End: 2015-10-31Target: 140Updated: 2013-11-07

Unknown Phase

Comparative Effectiveness and Cost-Benefit Analysis of Vancomycin Powder in High Risk Spine Surgery Patients
WithdrawnNCT01566422
Vanderbilt University Medical CenterSurgical Site Infection
Start: 2012-06-30End: 2014-12-31Updated: 2018-04-20
Evaluating the Efficacy and Safety of Intra-wound Vancomycin Powder in High Risk Patients
RecruitingNCT03839914
The University of Hong KongSpinal Deformity, Spinal Tumor, Surgical Site Infection +1
Start: 2020-08-01End: 2026-03-31Target: 76Updated: 2024-12-04