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Vagal Nerve Stimulation

DEVICE11 trials

Sponsors

Medtronic Cardiac Rhythm and Heart Failure, Stanford University, Queen Mary University of London, Maastricht University Medical Center, Riphah International University

Conditions

Gastro-Intestinal DisorderGastroparesisHealthy Adult ParticipantsInflammationIntestinal Barrier DysfunctionIrritable Bowel SyndromeMigrainePARKINSON DISEASE (Disorder)

Phase 1

Effects of Transvenous Vagus Nerve Stimulation on Immune Response: a Pilot Study
CompletedNCT01944228
Medtronic Cardiac Rhythm and Heart FailureInflammation
Start: 2013-08-31End: 2013-10-31Updated: 2013-10-31
Vagal Nerve Stimulation for Intestinal Barrier Dysfunction in Healthy Volunteers
CompletedNCT04061564
Queen Mary University of LondonIntestinal Barrier Dysfunction
Start: 2019-05-13End: 2019-09-15Updated: 2022-03-08

Unknown Phase

Vagal Nerve Stimulation for Gastroparesis
TerminatedNCT03120325
Stanford UniversityGastroparesis
Start: 2017-03-01End: 2018-08-24Updated: 2023-09-13
Vagal Nerve Stimulation in Irritable Bowel Syndrome
RecruitingNCT06090110
Maastricht University Medical CenterIrritable Bowel Syndrome
Start: 2023-12-01End: 2026-11-01Target: 166Updated: 2024-08-02
Vagal Nerve Stimulation and Pain Frequency, Intensity in Chronic Migraine
RecruitingNCT06191016
Riphah International UniversityMigraine
Start: 2023-12-26End: 2024-10-31Target: 128Updated: 2024-01-19
ABVN Phase 2-Studying the Effect of Stimulation on the Auricular Branch of the Vagal Nerve -B
CompletedNCT06827548
Indiana UniversityGastro-Intestinal Disorder, Gastroparesis
Start: 2021-05-13End: 2022-07-13Updated: 2025-02-14
Effects of Vagal Nerve Stimulation on Leg Muscle Activity and Posture in Parkinson's Disease
RecruitingNCT07226284
University of MinnesotaPARKINSON DISEASE (Disorder), Parkinson's Disease (PD)
Start: 2026-02-10End: 2029-01-01Target: 75Updated: 2026-02-13
Pain Neuroscience Education and Vagus Nerve Stimulation on Recovery in Individuals With Rheumatoid Arthritis
Not yet recruitingNCT07274124
Medipol UniversityRheumatic Diseases, Rheumatoid Arthritis (RA)
Start: 2026-01-31End: 2027-07-31Target: 36Updated: 2025-12-10
Exploring the Effect of taVNS on the Acute Stress Responses
CompletedNCT07628842
Daniel KeszthelyiHealthy Adult Participants
Start: 2025-03-21End: 2026-03-12Updated: 2026-06-05
Exploring the Role of taVNS in Nausea Management
RecruitingNCT07632456
Daniel KeszthelyiHealthy Adult Participants
Start: 2025-12-08End: 2026-09-01Target: 35Updated: 2026-06-08
The Effect of taVNS and Upper GI Motility
RecruitingNCT07632378
Daniel KeszthelyiHealthy Adult Participants
Start: 2025-02-25End: 2026-06-01Target: 12Updated: 2026-06-08

Related Papers

Transvenous vagus nerve stimulation does not modulate the innate immune response during experimental human endotoxemia: a randomized controlled study.
2015-06-0734 citations