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Vagal Nerve Simulation (VNS) Therapy
DEVICE
2 trials
Sponsors
Cyberonics, Inc.
, LivaNova
Conditions
Epilepsy
Partial Epilepsy
Treatment Resistant Depression
Phase 4
Study Comparing Best Medical Practice With or Without VNS Therapy in Pharmacoresistant Partial Epilepsy Patients
Terminated
NCT00522418
Cyberonics, Inc.
Epilepsy, Partial Epilepsy
Start: 2006-02-28
End: 2008-07-31
Updated: 2015-01-26
Unknown Phase
A Study to Assess Effectiveness and Efficiency of VNS Therapy in Patients With Difficult to Treat Depression.
Recruiting
NCT03320304
LivaNova
Treatment Resistant Depression
Start: 2017-12-14
End: 2031-12-01
Target: 500
Updated: 2026-08-27
Related Papers
Titration of vagus nerve stimulation for difficult-to-treat depression and onset of response: Early insights from the RESTORE-LIFE study.
2025-02-26
2 citations
Combination of Acute and Maintenance Esketamine Treatment With Adjunctive Long-Term Vagus Nerve Stimulation in Difficult-to-Treat Depression
Neuromodulation Technology at the Neural Interface
2024-02-10
2 citations
Invasive vagus nerve stimulation in a patient with treatment-resistant depression and Brugada Type-I electrocardiogram
Indian Journal of Psychiatry
2021-11-01
Vagus nerve stimulation as adjunctive therapy in patients with difficult-to-treat depression (RESTORE-LIFE): study protocol design and rationale of a real-world post-market study.
2020-09-29
16 citations