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V212

BIOLOGICAL6 trials

Sponsors

Merck Sharp & Dohme LLC

Conditions

Herpes ZosterHerpes Zoster-related Complications

Phase 1

A Study of an Investigational V212/Heat-Treated Varicella-Zoster Virus (VZV) Vaccine in Immunocompromised Adults (V212-002)
CompletedNCT00535236
Merck Sharp & Dohme LLCHerpes Zoster, Herpes Zoster-related Complications
Start: 2007-11-02End: 2010-01-26Updated: 2019-05-20
A Study to Evaluate Immunity to Varicella Zoster Virus After Immunization With V212 Vaccine or Zostavax (V212-003)
CompletedNCT00886613
Merck Sharp & Dohme LLCHerpes Zoster
Start: 2009-03-31End: 2009-12-31Updated: 2015-10-06
A Study to Evaluate the Safety and Immunogenicity of Inactivated Varicella-Zoster Virus (VZV) Vaccine in Adults With Hematologic Malignancies (HM) Receiving Treatment With Anti-Cluster of Differentiation (CD) 20 Monoclonal Antibodies (V212-013)
CompletedNCT01460719
Merck Sharp & Dohme LLCHerpes Zoster
Start: 2012-01-24End: 2012-09-25Updated: 2019-03-11

Phase 2

A Study to Evaluate the Safety and Immunogenicity of Inactivated Varicella Zoster Virus (VZV) Vaccine in Adults With Autoimmune Disease (V212-009)
CompletedNCT01527383
Merck Sharp & Dohme LLCHerpes Zoster
Start: 2012-02-21End: 2013-02-26Updated: 2019-01-14

Phase 3

A Study to Evaluate the Safety and Efficacy of Inactivated Varicella-zoster Vaccine (VZV) as a Preventative Treatment for Herpes Zoster (HZ) and HZ-related Complications in Participants Undergoing Hematopoietic Cell Transplants (HCTs) (V212-001)
CompletedNCT01229267
Merck Sharp & Dohme LLCHerpes Zoster
Start: 2010-11-30End: 2015-12-23Updated: 2019-09-30
A Study to Evaluate the Safety and Efficacy of Inactivated Varicella-zoster Vaccine (VZV) as a Preventative Treatment for Herpes Zoster (HZ) and HZ-related Complications in Adult Participants With Solid Tumor or Hematologic Malignancy (V212-011)
CompletedNCT01254630
Merck Sharp & Dohme LLCHerpes Zoster
Start: 2011-06-24End: 2017-04-11Updated: 2019-09-30

Related Papers

Immunogenicity of Inactivated Varicella Zoster Vaccine in Autologous Hematopoietic Stem Cell Transplant Recipients and Patients With Solid or Hematologic Cancer
Open Forum Infectious Diseases2020-06-0110 citations
Cost and utility in immunocompromised subjects who developed herpes zoster during the randomized V212 inactivated varicella-zoster vaccine (ZV<sub>IN</sub>) trial
Expert Review of Pharmacoeconomics & Outcomes Research2019-11-133 citations
Safety and efficacy of inactivated varicella zoster virus vaccine in immunocompromised patients with malignancies: a two-arm, randomised, double-blind, phase 3 trial.
2019-08-0629 citations
Inactivated varicella zoster vaccine in autologous haemopoietic stem-cell transplant recipients: an international, multicentre, randomised, double-blind, placebo-controlled trial.
2018-05-2469 citations
Safety and Immunogenicity of Inactivated Varicella-Zoster Virus Vaccine in Adults With Autoimmune Disease: A Phase 2, Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Clinical Infectious Diseases2017-05-3031 citations
Safety and immunogenicity of inactivated varicella-zoster virus vaccine in adults with hematologic malignancies receiving treatment with anti-CD20 monoclonal antibodies.
2017-03-0331 citations
A Phase III, Double-Blind, Randomized, Placebo-Controlled, Multicenter Clinical Trial to Study the Safety, Tolerability, Efficacy, and Immunogenicity of Inactivated Vzv Vaccine (ZVIN) in Recipients of Autologous Hematopoietic Cell Transplants (Auto-Hcts)
Biology of Blood and Marrow Transplantation2017-02-226 citations
Immunogenicity of Inactivated Varicella Zoster Vaccine (ZVIN) in Autologous Hematopoietic Stem Cell Transplant (auto-HSCT) Recipients
Open Forum Infectious Diseases2017-01-012 citations
Safety and Immunogenicity of Heat-Treated Zoster Vaccine (ZVHT) in Immunocompromised Adults
The Journal of Infectious Diseases2013-08-0178 citations