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Upadacitinib Placebo

DRUG5 trials

Sponsors

Abbvie Deutschland GmbH & Co. KG, AbbVie Deutschland GmbH & Co. KG, AbbVie

Conditions

Alopecia AreataGiant Cell ArteritisRheumatoid Arthritisnon-segmental vitiligo

Phase 3

A Phase 3b/4 Randomized, Double-Blind, Double-Dummy, Active-Comparator Controlled Study, Comparing the Efficacy and Safety of Upadacitinib Versus Adalimumab in Subjects with Moderate to Severe Rheumatoid Arthritis on a stable background of MTX and who had an Inadequate Response or Intolerance to a Single TNF Inhibitor (SELECT- SWITCH)
Active, not recruitingCTIS2022-502578-18-00
Abbvie Deutschland GmbH & Co. KGRheumatoid Arthritis
Start: 2023-11-07Target: 165Updated: 2025-09-16
A Phase 3 Randomized, Placebo-Controlled, Double-Blind Program to Evaluate Efficacy and Safety of Upadacitinib in Adult and Adolescent Subjects with Severe Alopecia Areata
Active, not recruitingCTIS2023-505061-82-01
AbbVie Deutschland GmbH & Co. KGAlopecia Areata
Start: 2024-06-17Target: 550Updated: 2025-11-04
A Phase 3, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Efficacy, Safety, and Tolerability of Upadacitinib in Adult and Adolescent Subjects with Non-Segmental Vitiligo Who Are Eligible for Systemic Therapy
Active, not recruitingCTIS2023-506195-27-00
AbbVie Deutschland GmbH & Co. KGnon-segmental vitiligo
Start: 2024-04-05Target: 239Updated: 2025-12-01
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Upadacitinib in Subjects with Giant Cell Arteritis
CompletedCTIS2023-505476-29-00
AbbVie Deutschland GmbH & Co. KGGiant Cell Arteritis
Start: 2019-04-05End: 2025-02-24Target: 201Updated: 2024-10-28
A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants in Japan With Alopecia Areata
RecruitingNCT07023302
AbbVieAlopecia Areata
Start: 2025-06-19End: 2029-02-28Target: 123Updated: 2025-12-24