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Unified Protocol (UP)

BEHAVIORAL5 trials

Sponsors

Boston University Charles River Campus, Butler Hospital, Massachusetts General Hospital, Universidad de Zaragoza, Karolinska Institutet

Conditions

AnxietyAnxiety DisordersDepressionEmotional DisorderGeneralized Anxiety Disorder (GAD)Implementation ScienceMood DisordersObsessive Compulsive Disorder

Unknown Phase

Efficacy Evaluation of a Unified Transdiagnostic Treatment for Anxiety Disorders
CompletedNCT01243606
Boston University Charles River CampusAnxiety Disorders, Mood Disorders
Start: 2010-12-31End: 2017-05-31Updated: 2017-10-09
Assisting Obsessive Compulsive Disorder (OCD) Patients With Discontinuing Long-term Serotonin Reuptake Inhibitors (SRIs)
CompletedNCT02103621
Butler HospitalObsessive Compulsive Disorder
Start: 2014-05-31End: 2018-01-31Updated: 2018-06-14
Study of a Transdiagnostic, Emotion-focused Group Intervention for Young Adults With Substance Use Disorders
CompletedNCT03315208
Massachusetts General HospitalAnxiety, Depression, Emotional Disorder +3
Start: 2017-11-22End: 2019-09-20Updated: 2021-04-01
Implementation of Two Transdiagnostic Interventions Based on Emotional Regulation (DBT and UP) for Alcohol Addiction
RecruitingNCT06366100
Universidad de ZaragozaImplementation Science
Start: 2024-02-01End: 2025-12-31Target: 160Updated: 2024-04-15
Metacognitive Therapy vs Unified Protocol for Patients With Comorbid Anxiety Disorders
Not yet recruitingNCT06971692
Karolinska InstitutetGeneralized Anxiety Disorder (GAD), Panic Disorder (With or Without Agoraphobia), Posttraumatic Stress Disorder (PTSD) +1
Start: 2025-08-31End: 2028-12-31Target: 114Updated: 2025-05-14

Related Papers

Implementation of two transdiagnostic interventions based on emotional regulation for professionals who treat alcohol addiction in the Spanish mental health system: A multicenter mixed methods pilot study protocol
PLoS ONE2025-05-09
SPIRIT checklist.
OPAL (Open@LaTrobe) (La Trobe University)2025-05-09
Study Protocol approved.
OPAL (Open@LaTrobe) (La Trobe University)2025-05-09
Changes in positive affect in cognitive-behavioral treatment of anxiety disorders.
2019-06-1711 citations
The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders Compared With Diagnosis-Specific Protocols for Anxiety Disorders
JAMA Psychiatry2017-08-02779 citations