Ultomiris 300 mg/3 mL concentrate for solution for infusion
Sponsors
Alexion Pharmaceuticals Inc., Regeneron Pharmaceuticals Inc.
Conditions
Generalized Myasthenia Gravis (gMG)Neuromyelitis Optica Spectrum Disorder (NMOSD)Paroxysmal nocturnal haemoglobinuria (PNH)Treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH) or Atypical Hemolytic Uremic Syndrome (aHUS)
Phase 2
Phase 3
A Phase 3, Open-label, Single-arm, Multicenter Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Efficacy, Safety, and Immunogenicity of Ravulizumab Administered Intravenously in Pediatric Participants (6 to < 18 years of age) with Generalized Myasthenia Gravis (gMG)
RecruitingCTIS2022-501882-29-00
Start: 2023-11-03Target: 4Updated: 2025-06-12
A Phase 3, Open-Label, Single-arm, Multicenter Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Activity, and Safety of Ravulizumab Administered Subcutaneously in Pediatric Participants (2 to < 18 years of age) with Paroxysmal Nocturnal Hemoglobinuria (PNH) or Atypical Hemolytic Uremic Syndrome (aHUS)
CompletedCTIS2022-502335-19-00
End: 2023-11-08Target: 14Updated: 2023-08-07
A Randomized, Open-Label, C5 Inhibitor-Controlled Study to Evaluate the Efficacy and Safety of Pozelimab and Cemdisiran Combination Therapy in Patients with Paroxysmal Nocturnal Hemoglobinuria who are Complement Inhibitor Treatment-Naive or Have Not Recently Received Complement Inhibitor Therapy
RecruitingCTIS2023-509657-31-00
Start: 2022-08-24Target: 17Updated: 2025-11-10