Tysabri

DRUG6 trials

Sponsors

Biogen, University at Buffalo, University of Chicago, Kessler Foundation

Conditions

Multiple SclerosisMultiple Sclerosis, Relapsing-RemittingProgressive Multifocal LeukoencephalopathyRelapsing-Remitting Multiple Sclerosis

Unknown Phase

Tysabri Observational Program

CompletedNCT00493298

BiogenRelapsing-Remitting Multiple Sclerosis

Start: 2007-06-29End: 2023-11-01Updated: 2024-04-08

Effect of Tysabri in Patients With Relapsing-Remitting Multiple Sclerosis: A Follow-up Magnetization Transfer Imaging (MTI) Study

CompletedNCT00937677

University at BuffaloMultiple Sclerosis

Start: 2007-11-30End: 2010-11-30Updated: 2011-09-07

Tysabri Effects on Cognition and Neurodegeneration in Multiple Sclerosis

CompletedNCT01071512

University of ChicagoMultiple Sclerosis

Start: 2010-04-30End: 2016-01-31Updated: 2017-10-25

Tysabri Observational Cohort Study - Multiple Sclerosis (MS) Registries

CompletedNCT03399981

BiogenProgressive Multifocal Leukoencephalopathy

Start: 2017-06-01End: 2023-12-31Updated: 2024-03-19

Examining Effects of Tysabri on Cognitive Fatigue Using fMRI

RecruitingNCT04565431

Kessler FoundationMultiple Sclerosis, Relapsing-Remitting

Start: 2021-03-19End: 2024-12-31Target: 25Updated: 2024-02-15

Pregnancy Exposure Registry for Vumerity (Diroximel Fumarate)

RecruitingNCT05658497

BiogenMultiple Sclerosis

Start: 2023-10-27End: 2032-07-06Target: 908Updated: 2025-08-01

Related Papers

No evidence for loss of natalizumab effectiveness with every-6-week dosing: a propensity score–matched comparison with every-4-week dosing in patients enrolled in the Tysabri Observational Program (TOP)

Therapeutic Advances in Neurological Disorders2021-01-0118 citations

Long-term safety and effectiveness of natalizumab treatment in clinical practice: 10 years of real-world data from the Tysabri Observational Program (TOP)

Journal of Neurology Neurosurgery & Psychiatry2020-03-31158 citations

Efficacy and safety of natalizumab in multiple sclerosis: interim observational programme results

Journal of Neurology Neurosurgery & Psychiatry2014-02-14171 citations