Tybost 150 mg film-coated tablets
Sponsors
Merck Sharp & Dohme LLC, University Hospital Maastricht, Fore Biotherapeutics Inc., Gilead Sciences Inc.
Conditions
HIV-1HIV-1 InfectionNon-Small Cell Lung Cancer with an EGFR driver mutation.Tumors harboring BRAF alterations
Phase 2
Modified osimertinib dosing, with or without cobicistat as a pharmacokinetic booster, to improve cost-effectiveness of advanced Non-Small Cell Lung Cancer treatment - OSIBOOST 2
RecruitingCTIS2023-505700-35-00
Start: 2024-07-16Target: 60Updated: 2025-06-10
A Phase 2 Master Protocol to assess the efficacy and safety of FORE8394, an inhibitor of BRAF Class 1 and Class 2 alterations, in participants with cancer harboring BRAF alterations
RecruitingCTIS2024-513578-23-00
Start: 2023-03-21Target: 129Updated: 2026-01-09
Phase 3
A Phase 3, Randomized, Active-Controlled, Open-Label Clinical Study to Evaluate a Switch to Doravirine/Islatravir (DOR/ISL 100 mg/0.25 mg) Once-Daily in Participants With HIV-1 Who Are Virologically Suppressed on Antiretroviral Therapy
WithdrawnCTIS2022-502127-22-00
Target: 110Updated: 2023-04-28
A Phase 3, Randomized, Open-label Study to Evaluate the Efficacy and Safety of Switching to a Regimen of Broadly Neutralizing
Antibodies Teropavimab and Zinlirvimab in Combination with Capsid Inhibitor Lenacapavir Twice Yearly in Virologically Suppressed Adults with HIV-1 Infection on Stable Oral Treatment Regimens
Not yet recruitingCTIS2025-524336-19-00
Target: 10Updated: 2026-07-21