Twinrix

BIOLOGICAL10 trials

Sponsors

University of North Carolina, Chapel Hill, Dartmouth-Hitchcock Medical Center, National Institute of Allergy and Infectious Diseases (NIAID), Aalborg University Hospital, GlaxoSmithKline

Conditions

Bipolar DisorderDepressionHIV InfectionsHepatitis AHepatitis BHepatitis CInfections, MeningococcalMalaria

Phase 1

Determining Responses to Two Different Vaccines in HIV and HCV Infected Individuals

CompletedNCT00393276

National Institute of Allergy and Infectious Diseases (NIAID)Hepatitis C, HIV Infections

Start: 2007-08-31End: 2009-07-31Updated: 2021-11-01

Study of the Safety and Immunogenicity of Pfs230D1M-EPA/Alhydrogel and Pfs25M-EPA/Alhydrogel , a Transmission Blocking Vaccine Against Plasmodium Falciparum Malaria, in Adults in the U.S. and Mali

CompletedNCT02334462

National Institute of Allergy and Infectious Diseases (NIAID)Malaria

Start: 2015-01-07End: 2018-10-22Updated: 2019-04-11

Phase 2

Effectiveness of Two Hepatitis B Vaccines in HIV-negative Youths

CompletedNCT00107042

University of North Carolina, Chapel HillHepatitis B

Start: 2004-02-29End: 2008-07-31Updated: 2017-03-29

Effectiveness of the Screen, Test, Immunize, Reduce Risk, and Refer (STIRR) Intervention for People With Both a Mental and Substance Abuse Disorder

CompletedNCT00316303

Dartmouth-Hitchcock Medical CenterBipolar Disorder, Depression, HIV Infections +3

Start: 2006-02-28End: 2012-08-31Updated: 2013-05-22

Phase 3

Hepatitis Vaccination in HIV Infection: Role of Adjuvant Interleukin-2

Aalborg University HospitalHepatitis A, Hepatitis B, HIV Infections

Start: 2007-03-31Target: 80Updated: 2007-11-01

Primary Study to Demonstrate Non-inferiority and Immunogenicity of GSK Biologicals' Meningococcal Vaccine 134612

CompletedNCT00465816

GlaxoSmithKlineInfections, Meningococcal

Start: 2007-04-11End: 2008-04-28Updated: 2018-06-08

Phase 4

Study to Show That the Combined Hepatitis A and B Vaccine is Non-inferior to Monovalent Vaccines in Adults

CompletedNCT00603252

GlaxoSmithKlineHepatitis A, Hepatitis B

Start: 2008-01-31End: 2008-06-30Updated: 2017-03-14

Evaluation of Immune Memory to Twinrix or Comparator by Challenge Dose Administration 4 Years After Primary Vaccination

CompletedNCT00684671

GlaxoSmithKlineHepatitis A, Hepatitis B

Start: 2008-05-26End: 2008-11-03Updated: 2018-08-17

Combination Hepatitis A and B Vaccine to Induce Immunity in Non-responders

WithdrawnNCT01126853

Mount Sinai Hospital, CanadaHepatitis B

Start: 2010-04-30End: 2011-07-31Updated: 2020-06-01

Cellular Immunity in Adult Hepatitis B-vaccinated Serologic Non-responders

University of AarhusHepatitis B

Start: 2011-10-31End: 2013-07-31Target: 400Updated: 2012-10-26

Related Papers

Malaria transmission-blocking vaccines Pfs230D1-EPA and Pfs25-EPA in Alhydrogel in healthy Malian adults; a phase 1, randomised, controlled trial.

2023-07-2438 citations

Immunological characterization of a VIR protein family member (VIR-14) in Plasmodium vivax-infected subjects from different epidemiological regions in Africa and South America

PLoS neglected tropical diseases2023-04-073 citations

Pfs230 yields higher malaria transmission–blocking vaccine activity than Pfs25 in humans but not mice

Journal of Clinical Investigation2021-02-09105 citations

"Spatial heterogeneity of environmental risk in randomized prevention trials: consequences and modeling".

2019-07-151 citations