TVI-Brain-1

BIOLOGICAL2 trials

Sponsors

TVAX Biomedical

Conditions

Glioblastoma MultiformeGlioblastoma Multiforme of BrainGrade IV AstrocytomaGrade IV Glioma

Phase 2

Study To Test the Safety and Efficacy of TVI-Brain-1 As A Treatment for Recurrent Grade IV Glioma

CompletedNCT01290692

TVAX BiomedicalGlioblastoma Multiforme, Grade IV Astrocytoma, Grade IV Glioma

Start: 2011-06-30End: 2014-02-28Updated: 2023-07-03

Study of Neoantigen-specific Adoptive T Cell Therapy for Newly Diagnosed MGMT Negative Glioblastoma Multiforme (GBM)

Active, not recruitingNCT05685004

TVAX BiomedicalGlioblastoma Multiforme of Brain

Start: 2023-09-15End: 2027-03-31Target: 120Updated: 2025-07-01

Related Papers

Initial analysis of adoptive neoantigen-specific T-cell immunotherapy for MGMT-unmethylated glioblastoma (TVI-AST-008): Signals amid control arm attrition.

Journal of Clinical Oncology2026-05-27