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TRX103

BIOLOGICAL3 trials

Sponsors

Tr1X, Inc., Quan Dong Nguyen

Conditions

Acute Lymphoblastic Leukemia, Adult B-CellAcute Lymphoblastic Leukemia, Adult T-CellAcute Myeloid Leukemia in RemissionCancer RemissionChronic Myelomonocytic Leukemia, in RemissionCrohns DiseaseGVHD, ChronicGVHD,Acute

Phase 1

Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)
RecruitingNCT06462365
Tr1X, Inc.Acute Lymphoblastic Leukemia, Adult B-Cell, Acute Lymphoblastic Leukemia, Adult T-Cell, Acute Myeloid Leukemia in Remission +8
Start: 2024-04-08End: 2027-04-15Target: 36Updated: 2025-04-15
Treatment of Moderate to Severe Refractory Crohn's Disease
RecruitingNCT06721962
Tr1X, Inc.Crohns Disease
Start: 2025-05-05End: 2027-01-30Target: 39Updated: 2025-12-10
A Proof-of-concept Trial to EvaluAte the efficaCy and Safety Of Cell Therapy TRX103 in Patients With Active, Non-infectious Uveitis
Not yet recruitingNCT07427628
Quan Dong NguyenNon Infectious Uveitis
Start: 2026-03-01End: 2028-12-01Target: 18Updated: 2026-02-23

Related Papers

Engineering allogeneic type 1 regulatory T cells: a scalable, off-the-shelf platform for restoring immune tolerance
Frontiers in Immunology2026-07-09