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Trimethoprim-Sulfamethoxazole (TMP-SMX)

DRUG5 trials

Sponsors

Immtech Pharmaceuticals, Inc, University Hospital, Geneva, University of California, San Francisco, Anhui Provincial Hospital, Second Affiliated Hospital, School of Medicine, Zhejiang University

Conditions

Antibiotic ProphylaxisChronic Obstructive Pulmonary Disease (COPD)Feasibility Pilot StudyHIV InfectionsKidney TransplantKidney TransplantationMRSA InfectionPneumocystis Carinii Pneumonia

Phase 3

DB289 Versus TMP-SMX for the Treatment of Acute Pneumocystis Jiroveci Pneumonia (PCP)
TerminatedNCT00302341
Immtech Pharmaceuticals, IncHIV Infections, Pneumocystis Carinii Pneumonia, Pneumonia, Interstitial Plasma Cell +1
Start: 2006-05-31End: 2008-12-31Updated: 2013-03-07

Phase 4

Randomized Clinical Trial to Compare a Regimen of Trimethoprim-sulfamethoxazole Plus Rifampicin With a Regimen of Linezolid in the Treatment of Methicillin-Resistant Staphylococcus Aureus (MRSA) Infection
CompletedNCT00711854
University Hospital, GenevaMRSA Infection
Start: 2009-01-31End: 2014-02-28Updated: 2014-08-05
Antibiotics for Kidney Transplant Recipients
Not yet recruitingNCT07106125
University of California, San FranciscoAntibiotic Prophylaxis, Feasibility Pilot Study, Kidney Transplant +2
Start: 2028-10-01End: 2033-12-01Target: 50Updated: 2026-09-11
Low- vs Standard-Dose TMP-SMX for Prevention of Pneumocystis Pneumonia After Kidney Transplantation
Not yet recruitingNCT07619027
Anhui Provincial HospitalKidney Transplantation, Pneumocystis Jirovecii Pneumonia
Start: 2026-06-01End: 2030-06-01Target: 1084Updated: 2026-06-01

Unknown Phase

Study on the Impact of Decolonization Treatment of Pneumocystis Jirovecii on the Frequency of Acute Exacerbation in COPD
Not yet recruitingNCT07665359
Second Affiliated Hospital, School of Medicine, Zhejiang UniversityChronic Obstructive Pulmonary Disease (COPD)
Start: 2026-07-01End: 2029-05-01Target: 630Updated: 2026-06-24

Related Papers

Randomized non-inferiority trial to compare trimethoprim/sulfamethoxazole plus rifampicin versus linezolid for the treatment of MRSA infection.
2014-09-1038 citations