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Trimethoprim Sulfamethoxazole

DRUG5 trials

Sponsors

University of Alberta, University of Pennsylvania, Corewell Health East, Indiana University, Monash University

Conditions

COPD Exacerbation AcuteCervical AdenitisFacial CellulitisGranulomatosis With PolyangiitisLeukemiaMastoiditisMethicillin Resistant Staphylococcus AureusMyeloma

Phase 1

TEMPO Study: Trimethoprim-Sulfamethoxazole in Granulomatosis With Polyangiitis
Active, not recruitingNCT03919435
University of PennsylvaniaGranulomatosis With Polyangiitis, Wegener Granulomatosis
Start: 2019-03-27End: 2027-12-30Updated: 2025-11-19
Treatment of Pneumocystis in COPD (the TOPIC Study)
TerminatedNCT05418777
Corewell Health EastCOPD Exacerbation Acute
Start: 2022-09-28End: 2022-12-19Updated: 2023-11-29

Phase 2

Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy Immunoglobulin Stopping or Extension (Stop Ig)
RecruitingNCT07202091
Monash UniversityLeukemia, Myeloma, Non Hodgkin's Lymphoma
Start: 2025-05-06End: 2027-03-31Target: 900Updated: 2025-10-07

Phase 3

Antibiotic Prophylaxis in Children With Pyelonephritis
WithdrawnNCT00752375
University of AlbertaPyelonephritis
Start: 2009-02-28End: 2014-12-31Updated: 2015-01-16

Phase 4

Trimethoprim-sulfamethoxazole vs. Clindamycin for the Treatment of Children With Invasive MRSA Infections
RecruitingNCT06982105
Indiana UniversityCervical Adenitis, Facial Cellulitis, Mastoiditis +6
Start: 2025-05-20End: 2027-06-30Target: 100Updated: 2025-06-04