Trientine

DRUG4 trials

Sponsors

National Center for Research Resources (NCRR), M.D. Anderson Cancer Center, Excelsior, Manchester University NHS Foundation Trust

Conditions

Advanced CancersHypertrophic CardiomyopathyTrientine Treatment for Wilson's DiseaseWilson Disease

Phase 1

Trientine and Carboplatin in Advanced Malignancies

CompletedNCT01178112

M.D. Anderson Cancer CenterAdvanced Cancers

Start: 2010-07-31End: 2014-08-31Updated: 2015-11-18

Phase 2

The Efficacy and Mechanism of Trientine in Patients With Hypertrophic Cardiomyopathy

CompletedNCT04706429

Manchester University NHS Foundation TrustHypertrophic Cardiomyopathy

Start: 2020-12-01End: 2024-07-30Updated: 2025-09-29

Phase 3

Study of Tetrathiomolybdate in Patients With Wilson Disease

CompletedNCT00004339

National Center for Research Resources (NCRR)Wilson Disease

Start: 1994-01-31Target: 90Updated: 2006-05-09

Unknown Phase

A Retrospective Study to Assess the Clinical Efficacy and Safety of Trientine in Wilson's Disease Patients

CompletedNCT03299829

ExcelsiorTrientine Treatment for Wilson's Disease

Start: 2018-01-10End: 2019-12-30Updated: 2020-08-18

Related Papers

Trientine for hypertrophic cardiomyopathy: a phase 2 trial.

2026-07-15

Rationale and design of a randomised trial of trientine in patients with hypertrophic cardiomyopathy

Heart2023-05-0315 citations

A Dose Escalation Study of Trientine Plus Carboplatin and Pegylated Liposomal Doxorubicin in Women With a First Relapse of Epithelial Ovarian, Tubal, and Peritoneal Cancer Within 12 Months After Platinum-Based Chemotherapy

Frontiers in Oncology2019-05-2434 citations

Overcoming platinum resistance through the use of a copper-lowering agent.

2012-04-0565 citations