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Transcatheter mitral valve repair

DEVICE8 trials

Sponsors

Montreal Heart Institute, Polares Medical SA, Shanghai Zhongshan Hospital, Michele De Bonis, HVR Cardio Oy

Conditions

Degenerative Mitral RegurgitationDegenerative Mitral Valve DiseaseFunctional Mitral RegurgitationHeart FailureMitral RegurgitationMitral Valve (MV) RegurgitationMitral Valve RegurgitationMitral Valve Regurgitation (Degenerative or Functional)

Unknown Phase

MitraClip for the Treatment of Moderate Functional Mitral Regurgitation: EVOLVE-MR
NCT03705312
Montreal Heart InstituteHeart Failure, Mitral Regurgitation, Mitral Valve Regurgitation Due to Cardiomyopathy (Disorder)
Start: 2019-02-22End: 2022-01-31Target: 174Updated: 2019-08-14
Early Feasibility Study of the PLAR Implant and Delivery System to Treat Functional Mitral Regurgitation ( EXPLORE FMR )
WithdrawnNCT04666467
Polares Medical SAFunctional Mitral Regurgitation
Start: 2021-04-01End: 2022-12-31Updated: 2023-12-20
Early Feasibility Study of the PLAR Implant and Delivery System to Treat Degenerative Mitral Regurgitation
TerminatedNCT04666480
Polares Medical SADegenerative Mitral Valve Disease
Start: 2021-04-30End: 2022-12-31Updated: 2023-12-20
The Multicenter Clinical Trial of a Novel TEER Decive (V-CLASP Trial)
NCT05391802
Shanghai Zhongshan HospitalMitral Regurgitation
Start: 2022-06-30End: 2024-06-30Target: 120Updated: 2022-05-26
Validation of the EuroSCORE II in Open and Trans-catheter Mitral Valve Repair.
CompletedNCT05714228
Michele De BonisMitral Valve Regurgitation
Start: 2020-06-10End: 2020-06-10Updated: 2023-02-06
Mitral Annular Repair With the CathHELIX™ Transcatheter System in Subjects With FMR
RecruitingNCT07188233
HVR Cardio OyMitral Valve Regurgitation (Degenerative or Functional)
Start: 2024-11-16End: 2026-07-31Target: 5Updated: 2025-09-23
FIH ITA Study - Vesalius TMVr System for Symptomatic Degenerative Mitral Regurgitation
RecruitingNCT07470788
Vesalius Cardiovascular Inc.Degenerative Mitral Regurgitation
Start: 2026-08-01End: 2032-04-01Target: 5Updated: 2026-08-19
A Prospective, Multicenter, Single-Arm Study to Support the Clinical Evidence Base for MRace as a Treatment Option for FMR Patients With Complex M-TEER Anatomies (AU)
Not yet recruitingNCT07757698
Polares Medical SAMitral Valve (MV) Regurgitation
Start: 2026-11-01End: 2032-12-01Target: 15Updated: 2026-08-11