TPI-287 20 mg/m2

DRUG2 trials

Sponsors

University of California, San Francisco

Conditions

Alzheimer's DiseaseCorticobasal Degeneration (CBD)Corticobasal Syndrome (CBS)Primary Four Repeat Tauopathies (4RT)Progressive Supranuclear Palsy (PSP)

Phase 1

A Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy Study of TPI-287 in Alzheimer's Disease

CompletedNCT01966666

University of California, San FranciscoAlzheimer's Disease

Start: 2013-11-30End: 2019-09-30Updated: 2020-04-14

Safety Study of TPI-287 to Treat CBS and PSP

CompletedNCT02133846

University of California, San FranciscoCorticobasal Degeneration (CBD), Corticobasal Syndrome (CBS), Primary Four Repeat Tauopathies (4RT) +1

Start: 2014-05-31End: 2019-09-30Updated: 2020-04-15

Related Papers

Reactions to Multiple Ascending Doses of the Microtubule Stabilizer TPI-287 in Patients With Alzheimer Disease, Progressive Supranuclear Palsy, and Corticobasal Syndrome

JAMA Neurology2019-11-11118 citations