Total Mesorectal Excision (TME)

PROCEDURE7 trials

Sponsors

Beth Israel Medical Center, Grupo Espanol Multidisciplinario del Cancer Digestivo, European Association for Endoscopic Surgery, Seoul National University Hospital, Peking University Cancer Hospital & Institute

Conditions

Locally Advanced Rectal CancerRECTAL CANCERRectal CancerRectal Cancer, AdenocarcinomaRectal NeoplasmsRectum Cancer

Phase 2

Neo-Adjuvant FOLFOX for Rectal Carcinoma

TerminatedNCT00832299

Beth Israel Medical CenterRectal Neoplasms

Start: 2009-01-31End: 2011-08-31Updated: 2018-03-01

Study of Neoadjuvant CT With Selective Radiotherapy in Patients With Intermediate-Risk Cancer Rectum

CompletedNCT00909987

Grupo Espanol Multidisciplinario del Cancer DigestivoRectum Cancer

Start: 2009-03-31End: 2013-06-30Updated: 2013-10-11

Brachytherapy Followed by Nivolumab Prior to Surgery in Rectal Cancer

Not yet recruitingNCT07645118

Dr. Te VuongLocally Advanced Rectal Cancer

Start: 2026-07-01End: 2030-12-01Target: 10Updated: 2026-06-12

Phase 3

Neoadjuvant Radiotherapy Followed by Transanal Endoscopic Microsurgery for T1-T2 Extraperitoneal Rectal Cancer

CompletedNCT02127645

European Association for Endoscopic SurgeryRECTAL CANCER

Start: 2011-06-30End: 2014-05-31Updated: 2018-07-26

Phase 4

Next Generation STAR-TREC (NG-ST) - Organ Preservation in Early Rectal Cancer

Not yet recruitingNCT07483060

Vastra Gotaland RegionRectal Cancer

Start: 2026-03-12End: 2031-12-01Target: 90Updated: 2026-03-19

Unknown Phase

Comparison Between Tailored Surgery Versus Total Mesorectal Excision in ycT2-3N0M0

TerminatedNCT05164315

Seoul National University HospitalRectal Cancer, Adenocarcinoma

Start: 2022-01-03End: 2024-08-26Updated: 2024-12-05

Organ Preservation First Strategy and Intentional Watch and Wait for MRI Defined Low-risk Rectal Cancer

RecruitingNCT06209099

Peking University Cancer Hospital & InstituteRectal Cancer

Start: 2024-01-17End: 2025-11-01Target: 96Updated: 2025-06-12

Related Papers

Radiologic and pathologic prognostic factors after neoadyuvant chemotherapy for T3 rectal cancer (RC): 3-year update GEMCAD 0801-trial.

Journal of Clinical Oncology2015-01-201 citations