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Toraymyxin PMX-20R (PMX Cartridge)
DEVICE
2 trials
Sponsors
Spectral Diagnostics (US) Inc.
Conditions
COVID
Corona Virus Infection
Endotoxemia
Sepsis, Severe
Septic Shock
Unknown Phase
Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Septic Shock
Completed
NCT01046669
Spectral Diagnostics (US) Inc.
Endotoxemia, Septic Shock
Start: 2010-06-30
End: 2017-06-30
Updated: 2019-02-26
Evaluating the Use of Polymyxin B Cartridge Hemoperfusion for Patients With Septic Shock and COVID 19
NCT04352985
Spectral Diagnostics (US) Inc.
Corona Virus Infection, COVID, Endotoxemia +2
Updated: 2021-09-20
Related Papers
Pathogen characteristics are key determinants of distinct host response phenotypes of sepsis.
2026-03-16
Polymyxin B hemoperfusion in endotoxemic septic shock patients without extreme endotoxemia: a post hoc analysis of the EUPHRATES trial
Intensive Care Medicine
2018-11-23
222 citations
Effect of Targeted Polymyxin B Hemoperfusion on 28-Day Mortality in Patients With Septic Shock and Elevated Endotoxin Level
JAMA
2018-10-09
447 citations
Efficacy of polymyxin B-immobilized fiber hemoperfusion for patients with septic shock caused by Gram-negative bacillus infection
PLoS ONE
2017-03-30
12 citations
The EUPHRATES trial (Evaluating the Use of Polymyxin B Hemoperfusion in a Randomized controlled trial of Adults Treated for Endotoxemia and Septic shock): study protocol for a randomized controlled trial.
2014-06-11
69 citations