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Tocilizumab Injection

DRUG5 trials

Sponsors

Tianjin Medical University General Hospital, National Cancer Institute, Naples, Abderrahmane Mami Hospital, Pirogov Russian National Research Medical University, Tang-Du Hospital

Conditions

COVID-19COVID-19 PneumoniaCOVID19Intensive Care UnitMild to ModerateMyasthenia Gravis, GeneralizedNeuromyelitis OpticaNeuromyelitis Optica Spectrum Disorders

Phase 2

Tocilizumab vs Azathioprine in Neuromyelitis Optica Spectrum Disorders
CompletedNCT03350633
Tianjin Medical University General HospitalNeuromyelitis Optica, Neuromyelitis Optica Spectrum Disorders
Start: 2017-11-01End: 2019-09-01Updated: 2019-10-24
Tocilizumab in COVID-19 Pneumonia (TOCIVID-19)
NCT04317092
National Cancer Institute, NaplesCOVID-19 Pneumonia
Start: 2020-03-19End: 2023-12-19Updated: 2023-03-24
Open-Label Extension of Tocilizumab in Subjects With Generalized Myasthenia Gravis
RecruitingNCT05716035
Tang-Du HospitalMyasthenia Gravis, Generalized
Start: 2023-04-01End: 2024-12-31Target: 64Updated: 2024-01-22

Phase 3

Assessment of Efficacy and Safety of Tocilizumab Compared to DefeROxamine, Associated With Standards Treatments in COVID-19 (+) Patients Hospitalized In Intensive Care in Tunisia
NCT04361032
Abderrahmane Mami HospitalCOVID19, Intensive Care Unit
Start: 2020-09-04End: 2020-10-04Target: 260Updated: 2020-08-27

Unknown Phase

COVID-19 Study at the Russian Clinical and Research Center of Gerontology of the Pirogov RNRMU
CompletedNCT05302947
Pirogov Russian National Research Medical UniversityCOVID-19, Mild to Moderate
Start: 2020-02-01End: 2021-06-30Updated: 2022-04-08

Related Papers

Rejuveinix Shows a Favorable Clinical Safety Profile in Human Subjects and Exhibits Potent Preclinical Protective Activity in the Lipopolysaccharide-Galactosamine Mouse Model of Acute Respiratory Distress Syndrome and Multi‐Organ Failure
Frontiers in Pharmacology2020-11-1021 citations
Tocilizumab for patients with COVID-19 pneumonia. The single-arm TOCIVID-19 prospective trial
Journal of Translational Medicine2020-10-21110 citations
A phase 2, open label, multicenter, single arm study of tocilizumab on the efficacy and tolerability of tocilizumab in the treatment of patients with COVID-19 pneumonia (TOCIVID-19 trial): Statistical analysis plan
Contemporary Clinical Trials Communications2020-10-0715 citations
TOCIVID-19 - A multicenter study on the efficacy and tolerability of tocilizumab in the treatment of patients with COVID-19 pneumonia. Study protocol
Contemporary Clinical Trials2020-10-0512 citations
Abstract CT405: Experience in using oncology drugs in patients with COVID-19
Cancer Research2020-08-151 citations
Safety and efficacy of tocilizumab versus azathioprine in highly relapsing neuromyelitis optica spectrum disorder (TANGO): an open-label, multicentre, randomised, phase 2 trial.
2020-05-01192 citations