FindTrial
Sign In

Tocilizumab 20 Mg/mL Intravenous Solution

DRUG3 trials

Sponsors

Christian Hassager, Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Conditions

Esophageal AdenocarcinomaGraves OphthalmopathyHeart ArrestOesophageal AdenocarcinomaOut-Of-Hospital Cardiac ArrestResectable CarcinomaSystemic Inflammatory Response Syndrome

Phase 2

IL-6 Inhibition for Modulating Inflammation After Cardiac Arrest
CompletedNCT03863015
Christian HassagerHeart Arrest, Out-Of-Hospital Cardiac Arrest, Systemic Inflammatory Response Syndrome
Start: 2019-03-04End: 2020-06-30Updated: 2020-08-21
Blood-borne Assessment of Stromal Activation in Esophageal Adenocarcinoma to Guide Tocilizumab Therapy
Active, not recruitingNCT04554771
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)Esophageal Adenocarcinoma, Oesophageal Adenocarcinoma, Resectable Carcinoma
Start: 2021-01-27End: 2028-04-10Updated: 2024-07-29
Tocilizumab in Active Moderate-severe Graves' Orbitopathy
NCT04876534
Fondazione IRCCS Ca' Granda, Ospedale Maggiore PoliclinicoGraves Ophthalmopathy
Start: 2019-12-18End: 2023-12-18Target: 64Updated: 2022-08-04

Related Papers

Modulation of inflammation by treatment with tocilizumab after out-of-hospital cardiac arrest and associations with clinical status, myocardial- and brain injury.
2022-12-2415 citations
Abstract 160: Associations Between Markers Of Inflammation And Myocardial Injury In Out-of-hospital Cardiac Arrest Patients After Treatment With Tocilizumab - A Sub Study Of The IMICA Trial
Circulation2022-11-08
Rationale and methods of the Antioxidant and NMDA receptor blocker Weans Anoxic brain damage of KorEa OHCA patients (AWAKE) trial.
2022-07-234 citations
Blood-borne assessment of stromal activation in esophageal adenocarcinoma to guide tocilizumab therapy: A randomized phase II proof-of-concept study (NCT04554771).
Journal of Clinical Oncology2022-06-01
Tocilizumab mitigates hypercoagulability after out-of-hospital cardiac arrest – results from a randomized controlled trial (IMICA)
European Heart Journal2021-10-01
The case for a stratified application of targeted agents against pancreatic cancer
EBioMedicine2021-04-241 citations
Tocilizumab reduces cardiac injury after out-of-hospital cardiac arrest primarily in patients without acute revascularization - Results from a randomized trial, The IMICA trial
European Heart Journal Acute Cardiovascular Care2021-04-01
Treatment Effects of Interleukin-6 Receptor Antibodies for Modulating the Systemic Inflammatory Response After Out-of-Hospital Cardiac Arrest (The IMICA Trial)
Circulation2021-03-22114 citations
Interleukin-6 Receptor Antibodies for Modulating the Systemic Inflammatory Response after Out-of-Hospital Cardiac Arrest (IMICA): study protocol for a double-blinded, placebo-controlled, single-center, randomized clinical trial.
2020-10-2011 citations