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TNT, TME, Surgery, radiation, chemotherapy

2 trials

Sponsors

Kagawa Yoshinori, Uemura Mamoru

Conditions

Rectal cancer local advanced rectal cancer, total neoadjuvant therapy, radiation therapy, chemotherapy, surgeryrectal cancer local advanced rectal cancer,radiation therapy,total neoadjuvant therapy,chemotherapy,surgery

Phase 2

A single center, phase 2 study to evaluate safety and efficacy of total neoadjuvant treatment of short course radiotherapy followed by chemotherapy, capecitabine combined with oxaliplatin (CAPOX) for locally advanced rectal cancer
Active, not recruitingJPRN-jRCTs051200113
Kagawa YoshinoriRectal cancer local advanced rectal cancer, total neoadjuvant therapy, radiation therapy, chemotherapy, surgery
Start: 2021-01-19Target: 27Updated: 2026-06-29
A multicenter single-arm P2 to evaluate safety and efficacy of the total neoadjuvant therapy for cT2 rectal cancer.
Active, not recruitingJPRN-jRCTs051230014
Uemura Mamorurectal cancer local advanced rectal cancer,radiation therapy,total neoadjuvant therapy,chemotherapy,surgery
Start: 2023-05-25Target: 45Updated: 2026-06-29

Related Papers

Circulating tumor DNA for predicting radiographic and pathologic response to total neoadjuvant therapy in locally advanced rectal cancer: ENSEMBLE-1.
Journal of Clinical Oncology2024-08-101 citations