TNK-tPA

DRUG3 trials

Sponsors

Boehringer Ingelheim, Beijing Tiantan Hospital, The First Affiliated Hospital of Zhengzhou University

Conditions

Acute Ischemic StrokeMyocardial Infarction

Phase 2

Tenecteplase Reperfusion Therapy in Acute Ischemic Cerebrovascular Events(TRACE)

CompletedNCT04676659

Beijing Tiantan HospitalAcute Ischemic Stroke

Start: 2018-05-12End: 2020-07-10Updated: 2020-12-21

Phase 3

Trial to Compare the Efficacy and Safety of a Single Bolus of TNK-tPA (Tenecteplase, Metalyse®) With Accelerated Infusion of Rt-PA (Alteplase, Actilyse®) in Asian Patients With Acute Myocardial Infarction

CompletedNCT00148460

Boehringer IngelheimMyocardial Infarction

Start: 2001-03-31End: 2006-02-28Target: 270Updated: 2013-10-29

Tenecteplase for Late-Window Stroke Guided by DWI-FLAIR Mismatch

Not yet recruitingNCT07540416

The First Affiliated Hospital of Zhengzhou UniversityAcute Ischemic Stroke

Start: 2026-05-01End: 2028-06-30Target: 564Updated: 2026-04-20

Related Papers

Safety and efficacy of tenecteplase versus alteplase in patients with acute ischaemic stroke (TRACE): a multicentre, randomised, open label, blinded-endpoint (PROBE) controlled phase II study

Stroke and Vascular Neurology2021-08-2498 citations