Tislelizumab Combined With Chemotherapy

DRUG4 trials

Sponsors

First Affiliated Hospital of Guangxi Medical University, Sun Yat-sen University, Chongqing University Cancer Hospital, AIO-Studien-gGmbH

Conditions

Extensive Stage Small Cell Lung Cancer (ES-SCLC)NSCLC (non-small Cell Lung Cancer)NSCLC, Stage IIIANon-small Cell Lung Cancer MetastaticRectal CancerRectal Cancer Stage IIRectal Cancer Stage III

Phase 2

The Effects of Neoadjuvant Tislelizumab Combined With Chemotherapy in Locally Advanced MSS Rectal Cancer

RecruitingNCT06254521

First Affiliated Hospital of Guangxi Medical UniversityRectal Cancer, Rectal Cancer Stage II, Rectal Cancer Stage III

Start: 2024-02-22End: 2027-12-30Target: 60Updated: 2024-02-12

Neoajuvant Tislelizumab Combined with Chemotherapy for Initially Unresectable Stage IIIA/N2 Non-small Cell Lung Cancer

Not yet recruitingNCT06614231

Sun Yat-sen UniversityNSCLC (non-small Cell Lung Cancer), NSCLC, Stage IIIA

Start: 2024-09-20End: 2028-09-08Target: 48Updated: 2024-09-26

Tislelizumab Combined With Chemotherapy Followed by Thoracic Consolidation Radiotherapy in the First-line Treatment of Extensive Stage Small Cell Lung Cancer

RecruitingNCT07425795

Chongqing University Cancer HospitalExtensive Stage Small Cell Lung Cancer (ES-SCLC)

Start: 2025-10-10End: 2028-07-31Target: 36Updated: 2026-02-23

Phase 3

Addition of Platinum-based Chemotherapy to Tislelizumab in PD-L1high Metastatic Non-small Cell Lung Cancer With a High Tumor Burden

Not yet recruitingNCT07715396

AIO-Studien-gGmbHNon-small Cell Lung Cancer Metastatic

Start: 2026-10-30End: 2031-10-30Target: 230Updated: 2026-07-22