TIOGUANINE
Sponsors
Karolinska University Hospital, Universitaetsklinikum Muenster AöR, Universitaetsklinikum Schleswig-Holstein, Universita Degli Studi Di Milano Bicocca, Medical University Of Silesia Katowice Poland
Conditions
Acute Lymphoblastic LeukaemiaAcute lymphoblastic leukemiaLymphoblastic lymphomaOncologyacute lymphoblastic leukemia in children and adolescents
Phase 1
Phase 2
ALLTogether1 - A Treatment Study Protocol of the ALLTogether Consortium for Children and Young Adults (0-45 Years of Age) with Newly Diagnosed Acute Lymphoblastic Leukaemia (ALL)
RecruitingCTIS2022-501050-11-01
Start: 2020-07-13Target: 5943Updated: 2025-12-17
Ruxolitinib for childhood ALL in Poland (Rux-cALL-Pol 2020 trial) - Single-arm interventional study with ruxolitinib and AIEOP-BFM 2017 Poland or AIEOP-BFM 2017 standard of care chemotherapy in children with acute lymphoblastic leukemia and confirmed activation of JAK/STAT pathway.
Not yet recruitingCTIS2024-518316-39-00
Target: 25Updated: 2025-04-04
Phase 3
LBL 2018 - International cooperative treatment protocol for children and adolescents with lymphoblastic lymphoma
RecruitingCTIS2023-508101-24-00
Start: 2019-08-01Target: 544Updated: 2026-01-23
AIEOP-BFM ALL 2017 - International collaborative treatment protocol for children and adolescents with acute lymphoblastic leukemia
Active, not recruitingCTIS2023-509856-32-00
Start: 2018-07-15Target: 4250Updated: 2025-08-19
International phase 3 trial in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) testing imatinib in combination with two different cytotoxic chemotherapy backbones
Active, not recruitingCTIS2024-515499-12-00
Start: 2017-10-02Target: 306Updated: 2024-11-12
Collaborative treatment protocol for children and adolescents with acute lymphoblastic leukemia. A randomized phase III study conducted in agreement with the AIEOP-BFM study group.
Active, not recruitingCTIS2024-517253-27-00
Start: 2021-07-01Target: 874Updated: 2024-10-28