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Tin Sn 117m Pentetate

RADIATION2 trials

Sponsors

National Cancer Institute (NCI)

Conditions

Anatomic Stage IV Breast Cancer AJCC v8Castration-Resistant Prostate CarcinomaMetastatic Breast CarcinomaMetastatic Lung Non-Small Cell CarcinomaMetastatic Malignant Neoplasm in the BoneMetastatic Prostate AdenocarcinomaStage IV Lung Cancer AJCC v8Stage IV Prostate Cancer AJCC v8

Phase 1

Testing the Safety of the Anti-cancer Drug, Sn-117m-DTPA, for Advanced Cancers That Have Spread to Bones
Not yet recruitingNCT06982222
National Cancer Institute (NCI)Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma, Metastatic Lung Non-Small Cell Carcinoma +4
Start: 2026-03-31End: 2027-02-12Target: 24Updated: 2026-04-03

Phase 2

Treatment of Cancer-Related Bone Pain by Using Bone-Targeted Radiation-Based Therapy (Sn-117m-DTPA) in Patients With Prostate Cancer That Has Spread to Bones
TerminatedNCT04616547
National Cancer Institute (NCI)Castration-Resistant Prostate Carcinoma, Metastatic Malignant Neoplasm in the Bone, Metastatic Prostate Adenocarcinoma +3
Start: 2021-12-18End: 2022-05-11Updated: 2025-10-03

Related Papers

ETCTN 10437: A single-arm phase II study of bone-targeted sn-117m-DTPA in symptomatic castration-resistant prostate cancer with skeletal metastases.
Journal of Clinical Oncology2022-06-01
A single arm phase II study of bone-targeted Sn-117 m-DTPA in symptomatic castration-resistant prostate cancer with skeletal metastases
BMC Cancer2022-04-152 citations