Tice
Sponsors
Merck Sharp & Dohme LLC, Swiss Cancer Institute
Conditions
Bladder CancerHigh Risk Non-muscle invasive bladder cancer
Phase 3
Biological Therapy in Treating Patients With Bladder Cancer
CompletedNCT00003779
Start: 1998-11-30End: 2010-06-30Updated: 2019-06-26
A Phase 3, Randomized, Comparator-controlled Clinical Trial to Study the Efficacy and Safety of Pembrolizumab (MK-3475) in combination with Bacillus Calmette-Guerin (BCG) in Participants with High-risk Non-muscle Invasive Bladder Cancer (HR NMIBC) that is either Persistent or Recurrent Following BCG Induction or that is Naïve to BCG Treatment (KEYNOTE-676)
Active, not recruitingCTIS2022-501817-29-00
Start: 2018-11-27Target: 559Updated: 2025-10-29