Ticagrelor monotherapy

DRUG4 trials

Sponsors

Yonsei University, University of Florida, Dong-A University, The First Affiliated Hospital with Nanjing Medical University

Conditions

Acute Coronary SyndromeCoronary Artery DiseaseDiabetes Mellitus, Type 2Intracranial AneurysmST Elevation Myocardial InfarctionStent Complication

Phase 4

Ticagrelor Monotherapy After 3 Months in the Patients Treated With New Generation Sirolimus Stent for Acute Coronary Syndrome (TICO Study)

Yonsei UniversityAcute Coronary Syndrome

Start: 2015-08-01End: 2023-05-31Target: 3056Updated: 2018-06-20

Ticagrelor With and Without Aspirin in Patients With Diabetes Mellitus

CompletedNCT04484259

University of FloridaCoronary Artery Disease, Diabetes Mellitus, Type 2

Start: 2021-03-31End: 2024-06-15Updated: 2025-03-30

3 Months Versus 12 Months Dual Antiplatelet Therapy After Drug-eluting Stent Implantation in STEMI

Dong-A UniversityST Elevation Myocardial Infarction

Start: 2021-01-01End: 2022-08-31Target: 1002Updated: 2020-12-22

Unknown Phase

Stent-Assisted Coiling Followed by Ticagrelor Monotherapy Instead of Dual Antiplatelet Therapy in Unruptured Intracranial Aneurysm

RecruitingNCT06015477

The First Affiliated Hospital with Nanjing Medical UniversityIntracranial Aneurysm, Stent Complication

Start: 2024-01-01End: 2025-07-01Target: 180Updated: 2024-03-13

Related Papers

Comparison of Short-term and Standard Duration Dual Antiplatelet Therapy in Elderly Patients: A Pooled Analysis of Five Korean Randomized Clinical Trials.

2025-07-142 citations

Clinical implication of ticagrelor monotherapy in patients with small vessel coronary artery disease: results from the TICO randomized trial

Frontiers in Cardiovascular Medicine2023-08-081 citations

Body mass index affecting ticagrelor monotherapy vs. ticagrelor with aspirin in patients with acute coronary syndrome: A pre-specified sub-analysis of the TICO randomized trial

Frontiers in Cardiovascular Medicine2023-03-305 citations

Ticagrelor Monotherapy After 3-Month Dual Antiplatelet Therapy in Acute Coronary Syndrome by High Bleeding Risk: The Subanalysis From the TICO Trial

Korean Circulation Journal2022-01-0124 citations

Ticagrelor Monotherapy Versus Ticagrelor With Aspirin in Acute Coronary Syndrome Patients With a High Risk of Ischemic Events

Circulation Cardiovascular Interventions2021-07-2024 citations

Impact of preprocedural coronary flow grade on duration of dual antiplatelet therapy in acute myocardial infarction

Scientific Reports2021-06-032 citations

Factors Related to Major Bleeding After Ticagrelor Therapy: Results from the TICO Trial

Journal of the American Heart Association2021-03-1920 citations

Ticagrelor Monotherapy Versus Ticagrelor With Aspirin in Patients With ST-Segment Elevation Myocardial Infarction.

2021-02-0120 citations

Ischemic and Bleeding Events of Ticagrelor Monotherapy in Korean Patients With and Without Diabetes Mellitus: Insights From the TICO Trial

Frontiers in Pharmacology2021-01-1417 citations

Effect of Ticagrelor Monotherapy vs Ticagrelor With Aspirin on Major Bleeding and Cardiovascular Events in Patients With Acute Coronary Syndrome

JAMA2020-06-16523 citations