Ticagrelor 90mg

DRUG20 trials

Conditions

Acute Coronary SyndromeAcute Myocardial InfarctionAntiplateletAntiplatelet TherapyArtery DiseaseAtherosclerosisCardiac DiseaseCerebral Infarction

Phase 1

A Study of the Effect of Epinephrine on Platelet Reactivity in Subjects Treated With Ticagrelor

CompletedNCT03441412

Vastra Gotaland RegionHealthy Volunteers

Start: 2018-02-28End: 2018-03-28Updated: 2018-05-11

Phase 2

Optical Coherence Tomography-Guided PCI With Single-Antiplatelet Therapy

CompletedNCT04766437

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)Non ST Segment Elevation Acute Coronary Syndrome

Start: 2021-02-19End: 2023-03-03Updated: 2023-03-06

Ticagrelor Monotherapy After Stenting

CompletedNCT05149560

Vastra Gotaland RegionAcute Myocardial Infarction

Start: 2021-12-14End: 2025-06-26Updated: 2026-03-20

Phase 3

Chronic Kidney Disease (CKD) Platelet Study

CompletedNCT03649711

University of ArkansasChronic Kidney Diseases, Heart Attack, Stroke, Ischemic

Start: 2018-11-01End: 2021-09-02Updated: 2022-12-29

The Value of Screening for HPR in Patients Undergoing Lower Extremity Arterial Endovascular Interventions

TerminatedNCT04007055

Marissa JarosinskiArtery Disease, Clopidogrel, Poor Metabolism of, Peripheral Arterial Occlusive Disease +2

Start: 2019-08-09End: 2024-03-28Updated: 2026-02-13

Evaluation of Safety and Efficacy of Two Ticagrelor-based De-escalation Antiplatelet Strategies in Acute Coronary Syndrome

NCT04718025

Collegium Medicum w BydgoszczyNSTEMI, STEMI, Unstable Angina

Start: 2022-02-07End: 2024-06-30Target: 4500Updated: 2023-04-21

Efficacy of Ticagrelor Plus Aspirin in Mild Non-cardioembolic Ischemic Stroke

CompletedNCT04738097

Mazandaran University of Medical SciencesIschemic Stroke, Transient Ischemic Attack

Start: 2021-08-08End: 2023-10-15Updated: 2023-10-19

Platelet Inhibition With Ticagrelor 60 mg Versus Ticagrelor 90 mg in Elderly Patients With ACS

CompletedNCT04739384

Federico II UniversityAcute Coronary Syndrome, Coronary Artery Disease, Myocardial Infarction +2

Start: 2021-04-01End: 2022-06-20Updated: 2022-07-07

Evaluation of Low Dose Colchicine and Ticagrelor in Prevention of Ischemic Stroke in Patients With Stroke Due to Atherosclerosis

RecruitingNCT05476991

Assistance Publique - Hôpitaux de ParisAtherosclerosis, Cardiac Disease, Cerebral Infarction +5

Start: 2023-05-17End: 2027-09-01Target: 2800Updated: 2025-09-08

Phase 4

Ticagrelor and Clopidogrel on Platelet Effects in Chinese Patients With Stable Coronary Artery Disease

CompletedNCT04001894

First Affiliated Hospital of Harbin Medical UniversityPlatelet Reactivity

Start: 2019-07-02End: 2020-12-09Updated: 2022-01-11

Ticagrelor Compared to Clopidogrel in Acute Coronary Syndromes

CompletedNCT04057300

McGill University Health Centre/Research Institute of the McGill University Health CentreAcute Coronary Syndrome

Start: 2018-10-01End: 2023-04-01Updated: 2023-11-03

LOwer Maintenance Dose TICagrelor in Acute Coronary Syndrome Patients Undergoing Percutaneous Coronary Intervention

NCT04060914

Beijing Anzhen HospitalAntiplatelet Therapy, Coronary Artery Disease, Percutaneous Coronary Intervention

Start: 2019-08-30End: 2021-12-30Target: 225Updated: 2019-08-19

A Study of Low and Standard-dose Ticagrelor After Intervention for ACS Patients

NCT04255602

Shanghai Tong Ren HospitalAcute Coronary Syndrome, Coronary Stent Implantation

Start: 2020-02-19End: 2024-12-31Target: 2120Updated: 2023-12-07

Unknown Phase

Impact of Ticagrelor Re-load on Pharmacodynamic Profiles

CompletedNCT01731041

University of FloridaCoronary Artery Disease

Start: 2013-01-31End: 2014-06-30Updated: 2015-06-10

Pharmacodynamic Evaluation of Switching From Prasugrel to Ticagrelor

CompletedNCT02016170

University of FloridaAcute Coronary Syndrome, Coronary Artery Disease

Start: 2014-03-31End: 2015-10-31Updated: 2024-07-03

In Vitro Pharmacodynamic Effects of Cangrelor in Ticagrelor Treated Patients

CompletedNCT02081443

University of FloridaCoronary Artery Disease

Start: 2014-04-30End: 2015-10-31Updated: 2017-04-04

Effect of Diabetes and Hepatic Enzymes Mutation on Clopidogrel VS Ticagrelor Activity in Myocardial Infarction (MI) Patients Undergoing Primary Percutaneous Coronary Intervention (PCI)

CompletedNCT03613857

Cairo UniversityMyocardial Infarction

Start: 2017-04-15End: 2018-07-28Updated: 2019-01-14

Replication of the PLATO Antiplatelet Trial in Healthcare Claims Data

CompletedNCT04237935

Brigham and Women's HospitalAntiplatelet

Start: 2019-09-22End: 2021-02-18Updated: 2023-07-27

Early Versus Late Loading of Ticagrelol in Patients With STEMI

NCT04267224

Assiut UniversityMyocardial Infarction

Start: 2020-03-01End: 2021-04-01Target: 800Updated: 2020-02-12

Replication of the ISAR-REACT 5 Antiplatelet Trial in Healthcare Claims Data

CompletedNCT05086081

Brigham and Women's HospitalAcute Coronary Syndrome

Start: 2020-10-10End: 2021-09-10Updated: 2023-07-27

2025-11-16

Ticagrelor Compared to Clopidogrel in Acute Coronary Syndromes trial (TC4): a Bayesian pragmatic cluster randomized controlled trial

Canadian Medical Association Journal2025-03-301 citations

Ticagrelor 60 vs. 90 mg in elderly ACS patients undergoing PCI: a randomized, crossover trial

European Heart Journal - Cardiovascular Pharmacotherapy2024-07-186 citations

Ticagrelor plus aspirin vs clopidogrel plus aspirin in mild non-cardioembolic ischemic stroke: A protocol of a randomized, controlled, active comparator arm, outcome assessor blind, feasibility study

Neurology Asia2023-09-01

Ticagrelor inhibits platelet aggregation and reduces inflammatory burden more than clopidogrel in patients with stages 4 or 5 chronic kidney disease.

2023-01-208 citations

A randomized non-inferiority study of low-dose and standard-dose ticagrelor after intervention for acute coronary syndrome: study protocol for the TIGER STUDY.

2022-03-05

Platelet Inhibition with Ticagrelor 60 mg Versus 90 mg Twice Daily in Elderly Patients with Acute Coronary Syndrome: Rationale and Design of the PLINY THE ELDER Trial.

2022-01-208 citations

A new approach to ticagrelor-based de-escalation of antiplatelet therapy after acute coronary syndrome. A rationale for a randomized, double-blind, placebo-controlled, investigator-initiated, multicenter clinical study

Cardiology Journal2021-06-0713 citations

Emulating Randomized Clinical Trials With Nonrandomized Real-World Evidence Studies

Circulation2020-12-17279 citations

Diabetes and CYP2C19 Polymorphism Synergistically Impair the Antiplatelet Activity of Clopidogrel Compared With Ticagrelor in Percutaneous Coronary Intervention–treated Acute Coronary Syndrome Patients

Journal of Cardiovascular Pharmacology2020-07-1617 citations

Adrenaline Improves Platelet Reactivity in Ticagrelor-Treated Healthy Volunteers

Thrombosis and Haemostasis2019-02-199 citations

Pharmacodynamic Effects of Switching From Prasugrel to Ticagrelor: Results of the Prospective, Randomized SWAP-3 Study.

2016-03-2127 citations

Pharmacodynamic Effects of Ticagrelor Dosing Regimens in Patients on Maintenance Ticagrelor Therapy: Results From a Prospective, Randomized, Double-Blind Investigation.

2015-06-244 citations