Thymosin alpha 1

DRUG11 trials

Conditions

2019 Novel Coronavirus InfectionChronic Hepatitis CEND STAGE RENAL DISEASEHematological MalignanciesLung AdenocarcinomaNon-small Cell Lung CancerPancreatitis, Acute NecrotizingResectable Non-Small-Cell Lung Cancer

Phase 1

Thymosin Alfa 1 in Recipients of Allogeneic Hematopoietic Transplantation for Hematological Malignancies

NCT00580450

University Of PerugiaHematological Malignancies

Start: 2007-12-31End: 2010-12-31Target: 9Updated: 2007-12-24

Phase 2

A Pilot Study to Evaluate ZADAXIN's® (Thymalfasin) Ability to Enhance Immune Response to the H1N1sw Influenza Vaccine

CompletedNCT01031966

sigma-tau i.f.r. S.p.A.END STAGE RENAL DISEASE

Start: 2009-11-30End: 2010-07-31Updated: 2012-03-29

Radiotherapy Combined With Thymosin for Metastatic NSCLC Patients Who Showed Stable Disease After First Line TKI Therapy

NCT02787447

First People's Hospital of HangzhouLung Adenocarcinoma

Start: 2016-05-31End: 2020-05-31Target: 46Updated: 2016-11-25

Study of Thymosin α1 to Reduce Acute Pneumonia For Bulky None-small Cell Lung Cancer

CompletedNCT03659578

Sun Yat-sen UniversityNon-small Cell Lung Cancer

Start: 2018-08-09End: 2021-09-30Updated: 2022-01-03

Phase 3

Thymosin Alpha-1 in Combination With Peg-Interferon Alfa- 2a and Ribavirin for the Therapy of Chronic Hepatitis C Nonresponsive to the Combination of IFN and Ribavirin.

CompletedNCT01178996

sigma-tau i.f.r. S.p.A.Chronic Hepatitis C

Start: 2004-12-31End: 2009-07-31Updated: 2010-08-10

The Efficacy and Safety of Ta1 for Sepsis

CompletedNCT02867267

Sun Yat-sen UniversitySepsis

Start: 2016-09-06End: 2021-03-23Updated: 2023-04-10

Experimental Trial of rhIFNα Nasal Drops to Prevent 2019-nCOV in Medical Staff

NCT04320238

Shanghai Jiao Tong University School of Medicine2019 Novel Coronavirus Infection

Start: 2020-01-21End: 2020-06-30Target: 2944Updated: 2020-03-31

Phase 4

Thymosin Alpha 1 in the Prevention of Pancreatic Infection Following Acute Necrotizing Pancreatitis

CompletedNCT02473406

Weiqin LiPancreatitis, Acute Necrotizing

Start: 2018-03-27End: 2021-03-24Updated: 2021-04-05

Efficacy of Thymosin Alpha 1 on Improving Monocyte Function for Sepsis

CompletedNCT02883595

Sun Yat-sen UniversitySepsis

Start: 2016-03-31End: 2016-12-31Updated: 2019-04-04

Unknown Phase

Efficacy of Thymosin alpha1 for Severe Sepsis

CompletedNCT00711620

Sun Yat-sen UniversitySevere Sepsis

Start: 2008-05-31End: 2011-01-31Updated: 2011-06-14

Neoadjuvant With Tα1 Plus Immuno-chemotherapy for Resectable NSCLC

Not yet recruitingNCT06607926

Xuanwu Hospital, BeijingResectable Non-Small-Cell Lung Cancer

Start: 2024-10-15End: 2025-12-30Target: 40Updated: 2024-09-23

BMJ2025-01-1515 citations

Immune-Enhancing Treatment among Acute Necrotizing Pancreatitis Patients with Metabolic Abnormalities: A <i>Post Hoc</i> Analysis of a Randomized Clinical Trial

Gut and Liver2024-02-151 citations

Association between pretreatment lymphocyte count and efficacy of immune-enhancing therapy in acute necrotising pancreatitis: a post-hoc analysis of the multicentre, randomised, placebo-controlled TRACE trial.

2023-03-244 citations

Thymosin alpha 1 therapy alleviates organ dysfunction of sepsis patients: a retrospective cohort study

Exploration of Immunology2022-04-222 citations

Thymosin alpha 1 in the prevention of infected pancreatic necrosis following acute necrotising pancreatitis (TRACE trial): protocol of a multicentre, randomised, double-blind, placebo-controlled, parallel-group trial

BMJ Open2020-09-0115 citations

The efficacy of thymosin alpha 1 for severe sepsis (ETASS): a multicenter, single-blind, randomized and controlled trial.

2013-01-1798 citations