THYMOGLOBULINE 5 mg/ml
Sponsors
Hospices Civils De Lyon, Centre Hospitalier Regional Universitaire De Tours, Assistance Publique Hopitaux De Paris, Institut Paoli-Calmettes, Itb-Med AB
Conditions
Acute myeloid leukemia (AML)High-risk myeloïd malignanciesKidney transplantMyelodysplastic syndrome (MDS)Renal Transplantationhaematological malignanciespediatric and adult patients undergoing HSC allograft procedures with Thymoglobulin® packaging
Phase 2
A 12-Month, Randomized, Controlled, Open-Label, Dose Escalation Study Evaluating Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of an Anti-CD2 Monoclonal Antibody, TCD601(siplizumab) Compared to Anti-Thymocyte Globulin (rATG), as Induction Therapy in de novo Renal Transplant Recipients
CompletedCTIS2023-507895-36-00
Start: 2021-06-06End: 2024-12-11Target: 33Updated: 2024-08-02
CASPER-ATG-IPC 2023-015 : Reinforced prophylaxis of GVH in elderly patients with haematological malignancies receiving haploidentical allogeneic hematopoietic stem cell transplantation: use of a low dose of post-allograft anti-lymphocytic serum.
RecruitingCTIS2023-506648-18-00
Start: 2025-01-14Target: 27Updated: 2025-12-04
AAA-IPC 2011-003 - Prospective and multicentre evaluation of 3 different doses of IV busulfan associated with fludarabine and thymoglobuline in the conditioning of allogeneic stem cell transplantation (SCT) from a matched related or unrelated donor in patients with poor prognosis myeloïd malignancies
Not yet recruitingCTIS2024-516435-27-00
Target: 177Updated: 2024-11-05
Phase 3
INduction in Sensitized kidney Transplant recipients without pre-Existing donor-specific AntiboDies: a randomized multicentre trial between a lymphocyte depleting and basiliximab (INSTEAD)
RecruitingCTIS2022-502007-30-00
Start: 2023-11-07Target: 244Updated: 2023-06-30
Phase III study comparing GVHD prophylaxis with ATG-thymoglobulin to ATLG-grafalon in elderly patients with acute myeloid leukemia or myelodysplastic syndrome and receiving an allogeneic hematopoietic stem cell transplantation with a 10/10 HLA matched unrelated donor following a reduced intensity conditioning regimen by fludarabine-treosulfan (OPTISAGE)
RecruitingCTIS2023-504555-27-00
Start: 2023-11-28Target: 324Updated: 2025-07-11