Therapeutic Surgical Procedure

PROCEDURE9 trials

Sponsors

Mayo Clinic, Vanderbilt-Ingram Cancer Center, SWOG Cancer Research Network, Pediatric Brain Tumor Consortium, National Cancer Institute (NCI)

Conditions

Anatomic Stage 0 Breast Cancer AJCC v8Anatomic Stage I Breast Cancer AJCC v8Anatomic Stage IA Breast Cancer AJCC v8Anatomic Stage IB Breast Cancer AJCC v8Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage IIA Breast Cancer AJCC v8Anatomic Stage IIB Breast Cancer AJCC v8Brain and Central Nervous System Tumors

Phase 1

Short-Course Chemoradiotherapy Followed by Chemotherapy for the Treatment of Resectable Gastric Adenocarcinoma

Active, not recruitingNCT04523818

M.D. Anderson Cancer CenterClinical Stage I Gastric Cancer AJCC v8, Clinical Stage IIA Gastric Cancer AJCC v8, Clinical Stage III Gastric Cancer AJCC v8 +13

Start: 2020-08-11End: 2028-12-31Updated: 2026-01-14

Evaluation of Abemaciclib and Radiation Therapy Before Surgery for the Treatment of High-Risk Adipocytic Retroperitoneal Sarcoma

RecruitingNCT06025747

University of WashingtonRetroperitoneal Sarcoma

Start: 2025-03-19End: 2029-03-03Target: 18Updated: 2026-03-30

Phase 2

Epirubicin, Docetaxel, and Capecitabine in Treating Women With Stage IIIA or Stage IIIB Breast Cancer

CompletedNCT00645866

Mayo ClinicBreast Cancer

Start: 2003-04-30End: 2006-03-31Target: 47Updated: 2011-05-16

S0713: Oxaliplatin, Capecitabine, Cetuximab, and RT Followed By Surgery in Pts W/Stage II or III Rectal Cancer

CompletedNCT00686166

SWOG Cancer Research NetworkColorectal Cancer

Start: 2009-02-28End: 2018-03-31Updated: 2018-05-18

Phase 3

Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma

Active, not recruitingNCT02306161

National Cancer Institute (NCI)Metastatic Ewing Sarcoma, Metastatic Malignant Neoplasm in the Bone, Metastatic Malignant Neoplasm in the Bone Marrow +3

Start: 2014-12-12End: 2026-09-17Updated: 2026-04-03

Unknown Phase

Paclitaxel and Radiation Therapy in Treating Patients Undergoing Surgery for Stage II or Stage III Breast Cancer

CompletedNCT00647218

Vanderbilt-Ingram Cancer CenterBreast Cancer

Start: 2000-02-29End: 2004-11-30Updated: 2017-02-23

Biomarkers in Blood Samples From Young Patients With Newly Diagnosed Brain Tumors Undergoing Standard Radiation Therapy and Chemotherapy

WithdrawnNCT01233479

Pediatric Brain Tumor ConsortiumBrain and Central Nervous System Tumors

Start: 2010-05-31End: 2017-08-24Updated: 2019-04-01

MRI and Gene Expression in Diagnosing Patients With Ductal Breast Cancer In Situ

Active, not recruitingNCT02352883

ECOG-ACRIN Cancer Research GroupDuctal Breast Carcinoma In Situ

Start: 2015-03-25End: 2027-11-30Updated: 2025-12-19

Radiation Therapy Boost Before Surgery for the Treatment of Non-metastatic Breast Cancer

Active, not recruitingNCT04871516

Rutgers, The State University of New JerseyAnatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8 +17

Start: 2021-05-18End: 2028-01-31Updated: 2026-01-22

Related Papers

Radiotherapy With a 12-Gene Expression Assay for Ductal Carcinoma In Situ: A Randomized Clinical Trial.

2025-12-01

Preoperative Radiation Boost Results in Low Rates of Re-excision and Reduced Locoregional Treatment Time in Breast Cancer Patients

Annals of Surgical Oncology2025-08-203 citations

Quality of Life Among Patients With Ductal Carcinoma In Situ

JAMA Network Open2025-07-03

Abstract P5-09-12: Pre-Operative Radiation Boost Planning in a Phase II Clinical Trial Achieves Acceptable Tumor Volume Coverage

Clinical Cancer Research2025-06-13

MRI-based Radiomic Features for Risk Stratification of Ductal Carcinoma in Situ in a Multicenter Setting (ECOG-ACRIN E4112 Trial).

2025-04-011 citations

Phase I trial of short-course chemoradiotherapy followed by chemotherapy as total neoadjuvant therapy for patients with potentially resectable gastric cancer.

Journal of Clinical Oncology2024-01-201 citations

Preoperative Breast MRI for Newly Diagnosed Ductal Carcinoma in Situ: Imaging Features and Performance in a Multicenter Setting (ECOG-ACRIN E4112 Trial)

Radiology2021-08-0334 citations

Association of Magnetic Resonance Imaging and a 12-Gene Expression Assay With Breast Ductal Carcinoma In Situ Treatment

JAMA Oncology2019-01-1731 citations

A phase II study of clinical activity of SCH 717454 (robatumumab) in patients with relapsed osteosarcoma and Ewing sarcoma

Pediatric Blood & Cancer2016-06-3096 citations

S0713: A phase II study of cetuximab (CET) added to induction chemotherapy (ICT) of oxaliplatin (OX) and capecitabine (CAP), followed by neoadjuvant chemoradiation (NACR) for locally advanced rectal cancer (LARC).

Journal of Clinical Oncology2015-05-203 citations