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The starting dose for all patients will be 90 mg/m2 I.V. over 0.5 hour every other day until CR is achieved (up to a maximum of 56 days elapsed time since the initiation of treatment). Depending upon the observed toxicity level and documented response level, study drug will be maintained at 90 mg/m2 throughout the induction period. However, dosage modifications will be implemented. During the Post-induction phase, the dose of Atragen will be maintained at the final dose during induction and will

2 trials

Sponsors

INSTITUTO DE ENFERMEDADES NEOPLASICAS,