Thalidomide (100mg)

DRUG3 trials

Sponsors

Shanghai Jiao Tong University School of Medicine, Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Conditions

Gastrointestinal Vascular MalformationLangerhans Cell HistiocytosisLangerhans Cell Histiocytosis (LCH)

Phase 2

Efficacy and Safety of Low-Dose Cytarabine Combined With Thalidomide in Adult Patients With Untreated LCH

RecruitingNCT07187193

Cancer Institute and Hospital, Chinese Academy of Medical SciencesLangerhans Cell Histiocytosis

Start: 2025-04-12End: 2027-04-13Target: 50Updated: 2025-09-22

Efficacy and Safety of XTD Regimen (Selinexor, Thalidomide and Dexamethasone) in Adult Patients With Relapsed/Refractory LCH

Active, not recruitingNCT07204041

Cancer Institute and Hospital, Chinese Academy of Medical SciencesLangerhans Cell Histiocytosis (LCH)

Start: 2025-08-01End: 2027-08-02Target: 40Updated: 2025-10-02

Phase 3

the Efficiency of Thalidomide for Recurrent Small Intestinal Bleeding Due to Gastrointestinal Vascular Malformation

CompletedNCT02707484

Shanghai Jiao Tong University School of MedicineGastrointestinal Vascular Malformation

Start: 2016-04-30End: 2021-04-30Updated: 2023-06-23

Related Papers

Thalidomide for Recurrent Bleeding Due to Small-Intestinal Angiodysplasia

New England Journal of Medicine2023-11-0151 citations