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Tenofovir DF

DRUG17 trials

Sponsors

National Cancer Institute (NCI), National Institute of Allergy and Infectious Diseases (NIAID), Gilead Sciences, Abbott, French National Agency for Research on AIDS and Viral Hepatitis

Conditions

Chronic Hepatitis BHBVHIV InfectionHIV InfectionsHIV SeronegativityHepatitis BLipodystrophyPregnancy

Phase 1

Tenofovir Disoproxil Fumarate to Treat Pediatric HIV
CompletedNCT00024986
National Cancer Institute (NCI)HIV Infection
Start: 2001-10-31End: 2005-09-30Target: 30Updated: 2008-03-04
A Dose Escalation Study of Tenofovir Alafenamide in Treatment-Naive Patients
CompletedNCT00036634
Gilead SciencesHIV Infections
Start: 2002-03-31End: 2003-02-28Updated: 2014-01-15

Phase 2

A Study to Compare Anti-HIV Drugs Given Twice a Day or Once a Day, With or Without Direct Observation
CompletedNCT00036452
National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections
End: 2006-01-31Updated: 2021-11-01
Effectiveness of ABT-378/Ritonavir Plus Lamivudine Plus Efavirenz Plus Tenofovir DF in HIV-Infected Patients
CompletedNCT00038220
AbbottHIV Infections
Start: 2000-07-31Target: 40Updated: 2006-07-27
Daily Tenofovir DF to Prevent HIV Infection Among Sex Workers in Cambodia
WithdrawnNCT00078182
National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections, HIV Seronegativity
Updated: 2016-12-14
Treatment of Persistent Viremia (Virus in Blood) in Chronic Hepatitis B Subjects Already Receiving Adefovir Dipivoxil
CompletedNCT00307489
Gilead SciencesChronic Hepatitis B
Start: 2006-03-31End: 2010-10-31Updated: 2011-11-01
A Study to Compare Tenofovir DF Versus the Combination of Emtricitabine Plus Tenofovir DF for the Treatment of Chronic Hepatitis B in Patients With Normal Alanine Aminotransferase (ALT)
CompletedNCT00507507
Gilead SciencesChronic Hepatitis B
Start: 2007-09-30End: 2012-08-31Updated: 2015-07-17
Study to Evaluate Changes in Limb Fat When Switching From a Thymidine Analogue
CompletedNCT00647946
Gilead SciencesLipodystrophy
Start: 2003-02-28End: 2006-02-28Updated: 2008-06-30
Rollover Protocol Continued Access to Tenofovir Disoproxil Fumarate (TDF) for Subjects in Taiwan
CompletedNCT01334567
Gilead SciencesHepatitis B
Start: 2010-08-31End: 2013-12-31Updated: 2014-03-04

Phase 3

Study of Lopinavir, Ritonavir, Tenofovir and Emtricitabine in HIV-Infected Antiretroviral Naïve Subjects
CompletedNCT00043966
AbbottHIV Infections
Start: 2002-07-31Target: 200Updated: 2006-07-27
Efficacy of Tenofovir-Emtricitabine and Efavirenz in HIV Infected Patients With Tuberculosis (ANRS129)
CompletedNCT00115609
French National Agency for Research on AIDS and Viral HepatitisHIV Infections, Tuberculosis
Start: 2006-01-31End: 2009-11-30Updated: 2011-12-22
Efficacy of Simplified Two Drug Kaletra Regimen vs. Kaletra Triple Drug Standard of Care Regimen in Treatment naïve HIV Infected Patients
CompletedNCT00234910
AbbottHIV Infection
Start: 2005-01-31End: 2008-06-30Updated: 2008-07-10
Safety and Efficacy of Tenofovir DF in HIV-1 Infected Adolescents Failing Their Current Antiretroviral Therapy
CompletedNCT00352053
Gilead SciencesHIV Infections
Start: 2006-06-30End: 2013-12-31Updated: 2015-07-14
Safety and Efficacy of Switching From Stavudine or Zidovudine to Tenofovir DF in HIV-1 Infected Children
CompletedNCT00528957
Gilead SciencesHIV Infections
Start: 2006-12-28End: 2017-08-16Updated: 2018-03-14
Study to Evaluate the Antiviral Efficacy, Safety and Tolerability of Tenofovir Disoproxil Fumarate Versus Placebo in Pediatric Participants With Chronic Hepatitis B Infection
Active, not recruitingNCT01651403
Gilead SciencesChronic Hepatitis B
Start: 2012-12-06End: 2027-07-01Updated: 2026-01-30

Phase 4

Prevention of Hepatitis B Virus Vertical Transmission by Serovaccination and Tenofovir During Pregnancy
CompletedNCT02039362
Hopital LariboisièreHBV, Pregnancy
Start: 2012-07-31End: 2016-07-31Updated: 2017-04-28
Utilization and Efficacy of Tenofovir DF in Adolescents With Chronic Hepatitis B Virus Infection
TerminatedNCT02479880
Gilead SciencesHepatitis B
Start: 2015-07-03End: 2018-04-11Updated: 2019-05-20

Related Papers

Prospective interventional study of tenofovir in pregnancy to prevent vertical transmission of hepatitis B in highly viremic women.
2017-03-0112 citations
Comparison of once-daily versus twice-daily combination antiretroviral therapy in treatment-naive patients: results of AIDS clinical trials group (ACTG) A5073, a 48-week randomized controlled trial.
2010-04-0137 citations
Decreased adherence to antiretroviral therapy observed prior to transient human immunodeficiency virus type 1 viremia.
2007-12-0165 citations