Tenofovir 1% vaginal gel

DRUG4 trials

Sponsors

National Institute of Allergy and Infectious Diseases (NIAID), CONRAD

Conditions

HIV InfectionsHIV PreventionPrevention

Phase 1

Blood Levels of Tenofovir Gel in HIV Uninfected Pregnant Women Planning Cesarean Delivery

CompletedNCT00540605

National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections

End: 2010-01-31Updated: 2021-10-25

Pharmacokinetic and Pharmacodynamic Study of Tenofovir 1% Gel

CompletedNCT01369303

CONRADPrevention

Start: 2012-01-31End: 2013-05-31Updated: 2013-12-12

Contraception and Menstrual Cycle Effect on Pharmacokinetics, Pharmacodynamics and Safety in Tenofovir Vaginal Gel Use

CompletedNCT01421368

CONRADHIV Prevention

Start: 2012-03-31End: 2014-03-31Updated: 2015-04-10

Phase 2

Safety and Effectiveness of TFV 1% Gel, TDF Tablets, and FTC/TDF Tablets in Preventing HIV in Women

CompletedNCT00705679

National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections

Start: 2009-08-31End: 2012-08-31Updated: 2021-10-29

Related Papers

Use of contraceptive depot medroxyprogesterone acetate is associated with impaired cervicovaginal mucosal integrity.

2018-09-1735 citations

Sharing of Investigational Drug Among Participants in the Voice Trial.

2016-11-012 citations

Stated product formulation preferences for HIV pre‐exposure prophylaxis among women in the VOICE‐D (MTN‐003D) study

Journal of the International AIDS Society2016-01-0184 citations

Divergent adherence estimates with pharmacokinetic and behavioural measures in the MTN‐003 (VOICE) study

Journal of the International AIDS Society2016-01-0152 citations

Risk of HIV-1 acquisition among women who use diff erent types of injectable progestin contraception in South Africa: a prospective cohort study.

2015-07-0143 citations

Pharmacological Measures of Treatment Adherence and Risk of HIV Infection in the VOICE Study

The Journal of Infectious Diseases2015-06-2943 citations

Tenofovir-Based Preexposure Prophylaxis for HIV Infection among African Women

New England Journal of Medicine2015-02-041278 citations

A multi-compartment, single and multiple dose pharmacokinetic study of the vaginal candidate microbicide 1% tenofovir gel.

2011-10-1987 citations

Pharmacokinetics and placental transfer of single-dose tenofovir 1% vaginal gel in term pregnancy.

2011-09-1919 citations