Tenapanor
Sponsors
Ardelyx, Kyle Staller, MD, MPH, Cedar Valley Digestive Health Center, University of Texas Southwestern Medical Center, Massachusetts General Hospital
Conditions
Chronic Kidney Disease Requiring Chronic DialysisConstipationConstipation Predominant Irritable Bowel SyndromeCystic FibrosisEnd Stage Renal DiseaseHyperoxaluriaHyperphosphatemiaIBS
Phase 1
Phase 2
Study to Evaluate the Efficacy of Tenapanor as Adjunctive Therapy to Phosphate Binder Therapy
CompletedNCT03824587
Start: 2019-02-28End: 2019-07-17Updated: 2023-03-06
Tenapanor in Synucleinopathy-Related Constipation
RecruitingNCT06460038
Start: 2025-01-01End: 2027-03-31Target: 30Updated: 2025-02-10
4-Week, Multi-center Dose-Ranging Study for the IBS-C in Pts. 6 to <12 Yrs
CompletedNCT06553547
Start: 2024-07-24End: 2026-07-07Updated: 2026-08-19
Phase 3
A 12-Week Study With a 4-Week Randomized Withdrawal Period to Evaluate the Efficacy and Safety of Tenapanor for the Treatment of IBS-C
CompletedNCT02621892
Start: 2015-10-31End: 2017-04-30Updated: 2020-04-21
An 8-Week Study to Evaluate Tenapanor in the Treatment of Hyperphosphatemia in End-Stage Renal Disease Patients on Hemodialysis (ESRD-HD)
CompletedNCT02675998
Start: 2016-01-31End: 2018-01-17Updated: 2020-08-10
A 26-Week Study to Evaluate the Efficacy and Safety of Tenapanor in IBS-C
CompletedNCT02686138
Start: 2015-12-31End: 2017-10-31Updated: 2020-04-22
A Long-Term Safety Study of Tenapanor for the Treatment of IBS-C
CompletedNCT02727751
Start: 2016-03-31End: 2017-10-31Updated: 2020-09-09
A Phase 3 Study of Tenapanor to Treat Hyperphosphatemia in ESRD Patients on Dialysis
CompletedNCT03427125
Start: 2018-01-08End: 2020-02-27Updated: 2023-06-29
Safety Study of Tenapanor for the Treatment of Pediatric Patients (6 to Less Than 18 Years Old) With IBS-C
Enrolling by invitationNCT05905926
Start: 2023-02-17End: 2031-10-01Target: 150Updated: 2026-06-04
Assessing Tenapanor as a Treatment of CF-related Constipation.
Active, not recruitingNCT06810167
Start: 2025-06-01End: 2027-06-30Updated: 2026-08-21
Phase 4
A Long-Term Study of Tenapanor Alone or in Combination With Sevelamer in Patients With CKD on Dialysis and HP
CompletedNCT03988920
Start: 2019-06-15End: 2021-07-31Updated: 2023-03-29
Study to Evaluate the Use of Tenapanor as Core Therapy in the Treatment of Hyperphosphatemia
CompletedNCT04549597
Start: 2020-11-20End: 2021-12-01Updated: 2023-03-29
Effect of Tenapanor on the Metagenomics and Metabolomics of Patients With Irritable Bowel Syndrome With Constipation
CompletedNCT05995899
Start: 2024-02-06End: 2025-12-17Updated: 2026-03-12
A Novel Approach for Reducing Hyperoxaluria and Kidney Stone Risk.
CompletedNCT06481150
Start: 2024-07-01End: 2025-09-14Updated: 2026-02-06
Related Papers
5 more papers not shown