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Tenapanor

DRUG15 trials

Sponsors

Ardelyx, Kyle Staller, MD, MPH, Cedar Valley Digestive Health Center, University of Texas Southwestern Medical Center, Massachusetts General Hospital

Conditions

Chronic Kidney Disease Requiring Chronic DialysisConstipationConstipation Predominant Irritable Bowel SyndromeCystic FibrosisEnd Stage Renal DiseaseHyperoxaluriaHyperphosphatemiaIBS

Phase 1

Phase 2

Phase 3

A 12-Week Study With a 4-Week Randomized Withdrawal Period to Evaluate the Efficacy and Safety of Tenapanor for the Treatment of IBS-C
CompletedNCT02621892
ArdelyxConstipation Predominant Irritable Bowel Syndrome
Start: 2015-10-31End: 2017-04-30Updated: 2020-04-21
An 8-Week Study to Evaluate Tenapanor in the Treatment of Hyperphosphatemia in End-Stage Renal Disease Patients on Hemodialysis (ESRD-HD)
CompletedNCT02675998
ArdelyxHyperphosphatemia
Start: 2016-01-31End: 2018-01-17Updated: 2020-08-10
A 26-Week Study to Evaluate the Efficacy and Safety of Tenapanor in IBS-C
CompletedNCT02686138
ArdelyxConstipation Predominant Irritable Bowel Syndrome
Start: 2015-12-31End: 2017-10-31Updated: 2020-04-22
A Long-Term Safety Study of Tenapanor for the Treatment of IBS-C
CompletedNCT02727751
ArdelyxConstipation Predominant Irritable Bowel Syndrome
Start: 2016-03-31End: 2017-10-31Updated: 2020-09-09
A Phase 3 Study of Tenapanor to Treat Hyperphosphatemia in ESRD Patients on Dialysis
CompletedNCT03427125
ArdelyxHyperphosphatemia
Start: 2018-01-08End: 2020-02-27Updated: 2023-06-29
Safety Study of Tenapanor for the Treatment of Pediatric Patients (6 to Less Than 18 Years Old) With IBS-C
Enrolling by invitationNCT05905926
ArdelyxIrritable Bowel Syndrome With Constipation (IBS-C)
Start: 2023-02-17End: 2031-10-01Target: 150Updated: 2026-06-04
Assessing Tenapanor as a Treatment of CF-related Constipation.
Active, not recruitingNCT06810167
Massachusetts General HospitalConstipation, Cystic Fibrosis
Start: 2025-06-01End: 2027-06-30Updated: 2026-08-21

Phase 4

Related Papers

5 more papers not shown