Telotristat etiprate
Sponsors
Lexicon Pharmaceuticals, Ipsen, Barbara Ann Karmanos Cancer Institute
Conditions
Carcinoid SyndromeDrug InteractionsHealthyHepatic ImpairmentMetastatic Nonfunctional Well Differentiated Neuroendocrine NeoplasmQT IntervalRenal ImpairmentUlcerative Colitis
Phase 1
A Open-Label Drug-Drug Interaction Study of Telotristat Etiprate and Midazolam in Healthy Subjects
CompletedNCT02147808
Start: 2014-05-31Updated: 2014-09-08
A Thorough QT Study of Telotristat Etiprate
CompletedNCT02155205
Start: 2014-05-31Updated: 2014-09-08
An Open-Label Food Effect Study of Telotristat Etiprate
CompletedNCT02157584
Start: 2014-06-30Updated: 2014-09-08
An Open-Label Drug-Drug Interaction Study of Telotristat Etiprate and Fexofenadine in Healthy Subjects
CompletedNCT02157558
Start: 2014-07-31Updated: 2014-09-08
Phase 1, Open-label, Drug-drug Interaction Study With Octreotide Acetate Injection and Telotristat Etiprate in Healthy Subjects
CompletedNCT02195635
Start: 2014-07-31Updated: 2016-09-07
Study to Evaluate a Dose of Telotristat Etiprate in Male and Female With Mild, Moderate and Severe Hepatic Insufficiency and Matched Healthy Subjects
CompletedNCT02683577
Start: 2016-02-29End: 2016-07-31Updated: 2019-01-25
Study to Compare a Dose of Telotristat Etiprate in Subjects With Renal Impairment With Matched Subjects With Normal Renal Function
CompletedNCT03442725
Start: 2018-02-09End: 2018-05-13Updated: 2020-04-08
Phase 2
Study of Telotristat Etiprate (LX1606) in Participants With Symptomatic Carcinoid Syndrome Not Managed by Stable-Dose Octreotide Therapy
CompletedNCT00853047
Start: 2009-03-31End: 2014-06-30Updated: 2018-12-26
Study of Telotristat Etiprate (LX1606) in Participants With Symptomatic Carcinoid Syndrome
CompletedNCT01104415
Start: 2010-06-15End: 2014-02-12Updated: 2019-03-15
A Study to Evaluate Safety and Efficacy of Telotristat Etiprate (LX1606) in Participants With Acute, Mild to Moderate Ulcerative Colitis
CompletedNCT01456052
Start: 2012-01-30End: 2013-09-03Updated: 2019-05-23
AMT-PET in Monitoring Telotristat Etiprate Treatment in Participants With MetastaticNeuroendocrine Neoplasm
CompletedNCT03453489
Start: 2018-06-20End: 2020-10-15Updated: 2025-04-10
Phase 3
TELESTAR (Telotristat Etiprate for Somatostatin Analogue Not Adequately Controlled Carcinoid Syndrome)
CompletedNCT01677910
Start: 2013-01-08End: 2016-03-21Updated: 2018-02-27
Telotristat Etiprate - Expanded Treatment for Patients With Carcinoid Syndrome Symptoms
CompletedNCT02026063
Start: 2014-01-14End: 2018-09-12Updated: 2019-09-17
Telotristat Etiprate for Carcinoid Syndrome Therapy
CompletedNCT02063659
Start: 2014-03-11End: 2016-03-29Updated: 2018-02-26