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Telisotuzumab Vedotin

DRUG11 trials

Sponsors

Abbvie Deutschland GmbH & Co. KG, AbbVie Deutschland GmbH & Co. KG, AbbVie, Jonsson Comprehensive Cancer Center

Conditions

Advanced Solid Tumors CancerLung Non-Small Cell CarcinomaNon Small Cell Lung CancerNon-Small Cell Lung CancerNon-Small Cell Lung Cancer (NSCLC)Non-small Cell Lung CancerPreviously Untreated MET Amplified Locally Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancerc-Met overexpressing EGFR wildtype non-squamous non-small cell lung cancer

Phase 1

Phase 2

Study of Telisotuzumab Vedotin (ABBV-399) in Participants With Previously Treated c-Met+ Non-Small Cell Lung Cancer
Active, not recruitingNCT03539536
AbbVieNon-small Cell Lung Cancer
Start: 2018-10-10End: 2026-08-31Updated: 2025-11-05
A Study to Assess Disease Activity of Intravenously (IV) Infused Telisotuzumab Vedotin in Adult Participants With Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
TerminatedNCT05513703
AbbVieNon Small Cell Lung Cancer
Start: 2022-11-21End: 2024-10-28Updated: 2025-10-24
Phase 2, Open-Label Study in Subjects with Previously Untreated MET Amplified Locally Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
CompletedCTIS2022-500608-23-00
Abbvie Deutschland GmbH & Co. KGPreviously Untreated MET Amplified Locally Advanced/Metastatic Non-Squamous Non-Small Cell Lung Cancer
Start: 2023-04-06End: 2024-10-28Target: 20Updated: 2024-08-29
Phase 2, Open-Label Safety and Efficacy Study of Telisotuzumab Vedotin (ABBV-399) in Subjects with Previously Treated c-Met+ Non-Small Cell Lung Cancer
Active, not recruitingCTIS2023-507902-15-00
AbbVie Deutschland GmbH & Co. KGNon-Small Cell Lung Cancer
Start: 2019-03-26Target: 67Updated: 2025-01-28
A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
RecruitingNCT06568939
AbbVieNon-Small Cell Lung Cancer
Start: 2025-01-20End: 2028-02-01Target: 150Updated: 2026-09-15
Telisotuzumab Vedotin and Osimertinib for the Treatment of Progressive, Incurable, Non Small Cell Lung Cancer
RecruitingNCT07323641
Jonsson Comprehensive Cancer CenterLung Non-Small Cell Carcinoma
Start: 2026-02-19End: 2028-02-01Target: 60Updated: 2026-04-20

Phase 3

Unknown Phase

Related Papers

5 more papers not shown