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telcagepant

DRUG5 trials

Sponsors

Merck Sharp & Dohme LLC

Conditions

Angina PectorisCalcitonin Gene-related Peptide ReceptorCerebrovascular AccidentCoronary Heart DiseaseHeart DiseaseMigraineMigraine DisordersPeripheral Vascular Diseases

Phase 1

A Study to Assess the Safety, Tolerability, and Effects of MK-0974 (Telcagepant) on Exercise Tolerance in Patients With Stable Angina (MK-0974-014)
CompletedNCT01294709
Merck Sharp & Dohme LLCAngina Pectoris, Calcitonin Gene-related Peptide Receptor, Coronary Heart Disease
Start: 2008-02-12End: 2009-03-13Updated: 2018-10-18
Positron Emission Tomography (PET) Study of Brain Calcitonin Gene-Related Peptide (CGRP) Receptor Occupancy After Telcagepant Administration (MK-0974-067)
CompletedNCT01315847
Merck Sharp & Dohme LLCMigraine
Start: 2010-01-14End: 2011-07-26Updated: 2019-04-02

Phase 2

A Study to Test the Safety and Effectiveness of MK-0974 (Telcagepant) Co-administered With Ibuprofen or Acetaminophen in Patients With Migraines With or Without Aura (MK-0974-046)
CompletedNCT00758836
Merck Sharp & Dohme LLCMigraine
Start: 2008-12-03End: 2009-08-24Updated: 2018-10-22
Telcagepant for Prevention of Menstrually Related Migraine in Female Participants With Episodic Migraine (MK-0974-065)
CompletedNCT01125774
Merck Sharp & Dohme LLCMigraine
Start: 2010-06-01End: 2011-04-08Updated: 2018-10-23

Phase 3

Telcagepant (MK-0974) Treatment of Migraine in Participants With Stable Vascular Disease (MK-0974-034)
CompletedNCT00662818
Merck Sharp & Dohme LLCCerebrovascular Accident, Heart Disease, Migraine Disorders +3
Start: 2008-03-17End: 2009-09-02Updated: 2018-10-19

Related Papers

Randomized controlled study of telcagepant plus ibuprofen or acetaminophen in migraine.
2011-04-0130 citations