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Tegoprazan 50 mg

DRUG8 trials

Sponsors

HK inno.N Corporation, Seoul National University Hospital, First People's Hospital of Hangzhou, Hanyang University Guri Hospital

Conditions

Cerebrovascular DiseaseGERD (Gastroesophageal Reflux Disease)Gastroesophageal Reflux DiseaseGastrointestinal BleedingGastrointestinal ComplicationHELICOBACTER PYLORI INFECTIONSHealthyIschemic Stroke

Phase 1

Effect of Tegoprazan on Pharmacodynamics of Clopidogrel in Healthy Male Participants
CompletedNCT03814642
HK inno.N CorporationHealthy
Start: 2019-01-21End: 2019-07-22Updated: 2019-10-21
Effect of Tegoprazan or RAPA113 on Pharmacodynamics/Pharmacokinetics of Clopidogrel in Healthy Male Volunteers
CompletedNCT04171687
HK inno.N CorporationHealthy
Start: 2019-10-21End: 2020-04-09Updated: 2020-05-08
Effect of Tegoprazan or RAPA114 on Pharmacokinetic of Atorvastatin in Healthy Adult Volunteers
CompletedNCT04221321
HK inno.N CorporationHealthy
Start: 2020-01-07End: 2020-04-20Updated: 2020-12-01
Study to Evaluate the Pharmacodynamics After Single Oral Dosing of Tegoprazan, EAPA115 and RAPA115 in Healthy Volunteers
CompletedNCT04231136
HK inno.N CorporationHealthy
Start: 2020-01-14End: 2020-08-03Updated: 2020-12-01
Study to Evaluate the Influence of Tegoprazan on the Pharmacokinetics of Proguanil in Healthy Volunteers
CompletedNCT04568772
Seoul National University HospitalGastroesophageal Reflux Disease
Start: 2020-11-25End: 2021-08-03Updated: 2021-09-27

Phase 3

Tegoprazan for Prevention of Gastrointestinal Complication in Ischemic Stroke Patients on Antiplatelet Therapy (TegoStroke)
RecruitingNCT07687706
Hanyang University Guri HospitalCerebrovascular Disease, Gastrointestinal Bleeding, Gastrointestinal Complication +3
Start: 2026-01-26End: 2027-12-01Target: 1524Updated: 2026-07-08

Phase 4

Tegoprazan Plus Amoxicillin BID vs TID Regimens for H. Pylori Eradication（Frequency Adjusted Same-dose Therapy for H. Pylori）
Not yet recruitingNCT07242443
First People's Hospital of HangzhouHELICOBACTER PYLORI INFECTIONS
Start: 2025-11-20End: 2026-12-31Target: 240Updated: 2025-11-21
A Study to Evaluate Tegoprazan as a Diagnostic Tool for GERD
Not yet recruitingNCT07826455
HK inno.N CorporationGERD (Gastroesophageal Reflux Disease)
Start: 2026-09-01End: 2028-07-31Target: 100Updated: 2026-09-17

Related Papers

Effect of <i>SLC22A1</i> polymorphism on the pharmacokinetics of proguanil in Korean: A semi‐physiologic population pharmacokinetic approach
Clinical and Translational Science2024-12-01
Evaluation of CYP2C19-Mediated Pharmacokinetic Drug Interaction of Tegoprazan, Compared with Vonoprazan or Esomeprazole.
2023-03-1016 citations