tegafur-uracil

DRUG13 trials

Sponsors

Memorial Sloan Kettering Cancer Center, Barbara Ann Karmanos Cancer Institute, Eastern Cooperative Oncology Group, Northwestern University, University of Pittsburgh

Conditions

Adult Hepatocellular CarcinomaAdverse Reaction to DrugBreast CancerColorectal CancerHead and Neck CancerMSI-L/MSSRecurrent Hepatocellular CarcinomaSquamous Cell Carcinoma of Oral Cavity

Phase 1

Combination Chemotherapy In Treating Patients With Advanced Cancer

CompletedNCT00003925

Barbara Ann Karmanos Cancer InstituteUnspecified Adult Solid Tumor, Protocol Specific

Start: 1998-05-31End: 2007-08-31Target: 36Updated: 2013-04-08

Combination Chemotherapy and Radiation Therapy in Treating Patients With Colorectal Cancer

CompletedNCT00002801

Memorial Sloan Kettering Cancer CenterColorectal Cancer

Start: 1996-04-30End: 2009-12-31Target: 30Updated: 2013-12-19

Combination Chemotherapy in Treating Patients With Advanced Solid Tumors

WithdrawnNCT00009815

University of PittsburghUnspecified Adult Solid Tumor, Protocol Specific

Start: 1999-12-31Updated: 2013-12-19

Paclitaxel Combined With Fluorouracil-Uracil and Leucovorin in Treating Patients With Solid Tumors

WithdrawnNCT00009828

University of PittsburghUnspecified Adult Solid Tumor, Protocol Specific

Start: 1999-12-31Updated: 2013-12-19

Phase 2

Fluorouracil-Uracil and Leucovorin in Treating Elderly Patients With Metastatic Colorectal Cancer

CompletedNCT00004860

Eastern Cooperative Oncology GroupColorectal Cancer

Start: 2000-10-09Updated: 2023-06-15

Fluorouracil-Uracil and Leucovorin in Treating Women With Metastatic Breast Cancer

TerminatedNCT00005608

Northwestern UniversityBreast Cancer

Start: 2000-02-29End: 2002-06-30Updated: 2012-06-06

Metronomic Chemotherapy With Tegafur/Uracil for Head and Neck Squamous Cell Carcinoma

Mackay Memorial HospitalHead and Neck Cancer

Start: 2008-12-31End: 2016-12-31Target: 115Updated: 2011-07-26

Oral Thalidomide and Tegafur-uracil to Decrease Hepatocellular Carcinoma Recurrence

CompletedNCT02447679

Chang Gung Memorial HospitalAdult Hepatocellular Carcinoma, Adverse Reaction to Drug, Recurrent Hepatocellular Carcinoma +1

Start: 2010-08-31End: 2017-02-02Updated: 2017-02-07

Maintenance Tegafur-uracil in Resected Oral Cavity Cancer With ECS+

Chang Gung Memorial HospitalSquamous Cell Carcinoma of Oral Cavity

Start: 2015-02-26End: 2020-05-11Target: 68Updated: 2019-02-12

Phase 3

S-1 or Tegafur-Uracil in Treating Patients With Previously Treated Stage III or Stage IV Head and Neck Cancer

Yokohama City UniversityHead and Neck Cancer

Start: 2006-04-30Target: 500Updated: 2013-05-15

Tegafur-Uracil and Leucovorin or S-1 in Treating Patients With Stage III Colon Cancer That Has Been Completely Removed by Surgery

CompletedNCT00660894

Translational Research Center for Medical Innovation, Kobe, Hyogo, JapanColorectal Cancer

Start: 2008-04-30End: 2015-07-31Updated: 2016-08-03

Phase 4

A Phase II Study of Tegafur-Uracil as Maintenance Chemotherapy in Patients With Stage II of Colon Cancer

National Taiwan University HospitalMSI-L/MSS, Stage II Colon Cancer

Start: 2014-09-30End: 2017-08-31Target: 300Updated: 2016-09-07

Unknown Phase

Maintenance Tegafur-uracil Versus Observation Following Adjuvant Oxaliplatin-based Regimen in Patients With Stage III Colon Cancer After Radical Resection

Kaohsiung Medical University Chung-Ho Memorial HospitalStage III Colon Cancer

Start: 2016-03-31End: 2024-02-29Target: 400Updated: 2017-02-08

Related Papers

Updated 5-year survival and exploratory T x N subset analyses of ACTS-CC trial: a randomised controlled trial of S-1 versus tegafur-uracil/leucovorin as adjuvant chemotherapy for stage III colon cancer.

2018-10-0713 citations

Maintenance tegafur-uracil versus observation following an adjuvant oxaliplatin-based regimen in patients with stage III colon cancer after radical resection: study protocol for a randomized controlled trial.

2017-04-261 citations

S-1 as adjuvant chemotherapy for stage III colon cancer: Updated outcomes of ACTS-CC trial.

Journal of Clinical Oncology2015-05-201 citations

Randomized Phase III Trial of Adjuvant Chemotherapy with S-1 after Curative Treatment in Patients with Squamous-Cell Carcinoma of the Head and Neck (ACTS-HNC)

PLoS ONE2015-02-1140 citations

S-1 as adjuvant chemotherapy for stage III colon cancer: a randomized phase III study (ACTS-CC trial).

2014-06-1879 citations