Tecartus 0.4 - 2 x 10e8 cells dispersion for infusion
Sponsors
Klinikum Der Universitat Munchen AöR, Kite Pharma Inc., Centre Hospitalier Universitaire De Saint Etienne, Universitair Ziekenhuis Gent
Conditions
Mantle Cell Lymphoma (MCL)Patients undergoing Fludarabine based lymphodepletion prior to CAR-T cell therapyRelapsed/Refractory B-precursor Acute Lymphoblastic Leukemia (r/r ALL) Relapsed/Refractory B-cell non-Hodgkin lymphoma (r/r NHL)Relapsed/Refractory Mantle Cell LymphomaSolid and Hematological Malignanciesfor hematological malignancyhematology
Phase 1
Phase 2
Long-term Follow-up Study for Participants of Kite-Sponsored Interventional Studies Treated With Gene-Modified Cells
RecruitingCTIS2023-507041-28-00
Start: 2022-11-28Target: 96Updated: 2025-09-23
A Phase 2 Multicenter Study Evaluating the Efficacy of KTE-X19 in Subjects with Relapsed/Refractory Mantle Cell Lymphoma (ZUMA-2)
CompletedCTIS2023-506641-35-00
Start: 2018-07-09End: 2025-06-17Target: 68Updated: 2025-03-10
Early treatment intensification in patients with high risk Mantle Cell Lymphoma using CAR-T-cell treatment after an abbreviated induction therapy with Rituximab and Ibrutinib and 6 months Ibrutinib maintenance (Arm A) as compared to standard of care induction and maintenance (Arm B)
RecruitingCTIS2022-502405-15-01
Start: 2024-04-08Target: 150Updated: 2026-01-22
Phase 4
Temporal characterization of Extracellular Vesicles during cellular therapy using CAR-T cells and during the occurrence of Immune effector Cell-Associated Neurotoxicity Syndrome : the VESICANS study
RecruitingCTIS2024-515328-35-00
Start: 2025-07-02Target: 60Updated: 2025-04-17
Fludarabine exposure in patients undergoing Fludarabine based lymphodepletion prior to CAR-T cell therapy
Not yet recruitingCTIS2025-524278-40-00
Target: 75Updated: 2026-03-23