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Tasigna 200 mg hard capsules

DRUG7 trials

Sponsors

Bluepharma Industria Farmaceutica S.A., Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Stichting, Centre Leon Berard, Masarykova Univerzita, Institut National De La Sante Et De La Recherche Medicale

Conditions

Advanced / Metastatic cancersAdvanced solid tumorChronic Myeloid LeukemiaChronic myeloid leukemiaMultiple myelomaNon-Hodgkin lymphomaPrimary Philadelphia-chromosome positive leukemia cells from chronic myelogenous leukemia (CML)T-cell prolymphocytic leukemia

Phase 1

Phase 2

A Dutch National Study on behalf of the Center for Personalized Cancer Treatment (CPCT) to Facilitate Patient Access to Commercially Available, Targeted Anti-cancer Drugs to determine the Potential Efficacy in Treatment of Advanced Cancers with a Known Molecular Profile: The Drug Rediscovery Protocol (DRUP trial)
RecruitingCTIS2023-509152-33-00
Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis StichtingAdvanced solid tumor, Multiple myeloma, Non-Hodgkin lymphoma +1
Start: 2016-07-25Target: 3000Updated: 2025-12-19
A phase II, single-arm study of de-escalation and treatment-free remission in patients with chronic myeloid leukemia treated with nilotinib in first-line therapy followed by a second attempt after nilotinib and asciminib combination: DANTE study
CompletedCTIS2024-516122-66-00
Novartis Farma S.p.A.Chronic myeloid leukemia
Start: 2019-01-18End: 2025-10-15Target: 170Updated: 2025-07-09
A Prospective Phase II Clinical Trial Evaluating the Efficacy and the Safety of Tyrosine Kinase Inhibitors Withdrawal After a Previous Two-step Dose Reduction in Patients With Chronic Myeloid Leukemia in Deep Molecular Remission
Active, not recruitingCTIS2024-514592-17-00
Masarykova Univerzitachronic myeloid leukemia
Start: 2020-06-16Target: 221Updated: 2025-11-06
MOST Plus (My Own Specific Treatment) - A two-period, multicenter, randomized, open-label, phase II study evaluating the clinical benefit of a maintenance treatment targeting tumor molecular alterations in patients with progressive locally-advanced or metastatic solid tumors
RecruitingCTIS2023-510566-27-00
Centre Leon BerardAdvanced / Metastatic cancers
Start: 2014-02-27Target: 900Updated: 2025-12-12

Phase 3

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