Tadekinig alfa
Sponsors
AB2 Bio S.A., AB2 Bio Ltd.
Conditions
18 driven monogenic autoinflammatory conditions: NLRC4 mutation and XIAP deficiencyNLRC4-MASXIAP Deficiency
Phase 3
Therapeutic Use of Tadekinig Alfa in NLRC4 Mutation and XIAP Deficiency
CompletedNCT03113760
Start: 2017-07-21End: 2023-11-02Updated: 2025-07-02
Therapeutic Use of Tadekinig Alfa in NLRC4 Mutation and XIAP Deficiency As Open Label Extension
CompletedNCT03512314
Start: 2018-01-24End: 2024-05-08Updated: 2025-03-17
Open-label extension study with Tadekinig alfa (r-hIL-18BP) to monitor safety and tolerability in patients with IL-18 driven monogenic autoinflammatory conditions: NLRC4 mutation and XIAP deficiency
CompletedCTIS2023-504534-21-00
Start: 2023-10-09End: 2024-05-08Target: 1Updated: 2023-11-14