T Cell-Depleted Hematopoietic Stem Cell Transplantation

BIOLOGICAL4 trials

Sponsors

Fred Hutchinson Cancer Center, University of Wisconsin, Madison, University of Nebraska

Conditions

Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Leukemia of Ambiguous LineageAcute Undifferentiated LeukemiaAdult Acute Lymphoblastic Leukemia in RemissionAdult Acute Myeloid Leukemia in RemissionBlast Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveChildhood Acute Lymphoblastic Leukemia in Remission

Phase 2

Selective Depletion of CD45RA+T Cells From Allogeneic Peripheral Blood Stem Cell Grafts for the Prevention of GVHD

TerminatedNCT00914940

Fred Hutchinson Cancer CenterGraft Versus Host Disease, Leukemia, Myelodysplastic Syndromes

Start: 2009-12-17End: 2020-05-26Updated: 2020-08-20

Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts in Preventing GVHD in Children

CompletedNCT01858740

Fred Hutchinson Cancer CenterAccelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia, Acute Leukemia of Ambiguous Lineage +15

Start: 2014-04-10End: 2023-07-30Updated: 2024-03-12

Enhancing Anti--Tetanus Vaccine Response After Autologous Stem Cell Transplantation

TerminatedNCT02700841

University of NebraskaPlasma Cell Myeloma

Start: 2020-01-09End: 2022-12-21Updated: 2024-03-12

Unknown Phase

TCR-α/β and CD19 Depleted Stem Cell Grafts From Haplo Donors for HSCT in Relapsed Lymphoma

CompletedNCT02652468

University of Wisconsin, MadisonLymphoma

Start: 2016-03-10End: 2021-09-17Updated: 2022-01-05

Related Papers

Memory CD4+ T Cells Recognize Divergent HLA-DP Immunopeptidomes and Contribute to Leukemia Control after Allogeneic HCT

Blood2024-11-051 citations

Zinc Status Affects T Cell Reconstitution in Patients Receiving Naïve T Cell Depleted Allogeneic HSCT

Blood2023-11-021 citations

Cellular Immunotherapies for Leukemia Patients

Oncology Times2017-01-10