Synvisc-One

DEVICE9 trials

Sponsors

Carbylan Therapeutics, Inc., Genzyme, a Sanofi Company, Nature Cell Co. Ltd., Kaohsiung Veterans General Hospital., Zimmer Biomet

Conditions

Intra-Articular InjectionKnee OsteoarthritisOsteoarthritisOsteoarthritis of the KneeOsteoarthritis, Knee

Phase 2

Hydros Joint Therapy and Hydros-TA Joint Therapy for Pain Associated With Knee Osteoarthritis (OA)

CompletedNCT01134406

Carbylan Therapeutics, Inc.Osteoarthritis of the Knee

Start: 2010-04-30End: 2011-10-31Updated: 2011-11-03

A Phase 2 Study to Evaluate the Efficacy and Safety of JointStem in Treatment of Osteoarthritis

CompletedNCT02674399

Nature Cell Co. Ltd.Osteoarthritis, Knee

Start: 2016-02-16End: 2018-12-28Updated: 2021-08-10

Comparing One Intraarticular Injection of a Novel HYAJOINT Plus With Synvisc-One for the Treatment of Knee OA

CompletedNCT02686047

Kaohsiung Veterans General Hospital.Knee Osteoarthritis

Start: 2014-09-30End: 2015-08-31Updated: 2016-02-19

Phase 4

Study of Safety and Efficacy of 6 mL Synvisc-One (Hylan G-F 20) in Indian Patients With Symptomatic Osteoarthritis of Knee(s) After Initial and Repeat Treatment

CompletedNCT02389452

Genzyme, a Sanofi CompanyOsteoarthritis

Start: 2010-02-28End: 2011-09-30Updated: 2017-08-07

Unknown Phase

nSTRIDE APS Versus Hyaluronic Acid for Knee Osteoarthritis

CompletedNCT03182374

Zimmer BiometOsteoarthritis, Knee

Start: 2017-07-14End: 2023-01-30Updated: 2024-09-19

Efficacy of OSTENIL PLUS (Hyaluronic Acid) Versus SYNVISC-ONE in Patients With Tibiofemoral Osteoarthritis

CompletedNCT03203408

TRB ChemedicaKnee Osteoarthritis

Start: 2011-06-21End: 2012-11-22Updated: 2017-10-11

Cellular Matrix Device for the Treatment of Mild to Moderate Knee Osteoarthritis

Regen Lab SAKnee Osteoarthritis

Start: 2017-07-18End: 2021-03-31Target: 190Updated: 2019-11-14

Treatment of Knee Osteoarthritis With PAAG-OA

Active, not recruitingNCT04045431

ConturaOsteoarthritis, Knee

Start: 2019-05-15End: 2026-11-30Target: 238Updated: 2024-01-08

Innovative Tool to Analyse Synovial Fluid of Patients With Knee Ostearthritis After IA Injection of Synvisc-one®

CompletedNCT04321668

PulsalysIntra-Articular Injection, Knee Osteoarthritis

Start: 2020-02-12End: 2022-02-15Updated: 2022-04-22

Related Papers

Sustained symptom relief and safety over five years following a single intra-articular injection of 2.5[%] polyacrylamide hydrogel in patients with knee osteoarthritis.

2026-03-04

Efficacy and safety of a combination of platelet-rich plasma with non-crosslinked hyaluronic acid versus a crosslinked hyaluronic acid, in single-injection for knee osteoarthritis. Randomized, controlled, multicenter, non-inferiority trial

BMC Musculoskeletal Disorders2026-02-24

Three-year follow-up from a randomised controlled trial of a single intra-articular polyacrylamide hydrogel injection in subjects with knee osteoarthritis.

2025-12-11

Safety and performance of Hydros and Hydros-TA for knee osteoarthritis: a prospective, multicenter, randomized, double-blind feasibility trial.

2015-03-1839 citations