Sym022

DRUG3 trials

Sponsors

Symphogen A/S

Conditions

LymphomaMetastatic CancerSolid Tumor

Phase 1

Sym021 Monotherapy, in Combination With Sym022 or Sym023, and in Combination With Both Sym022 and Sym023 in Patients With Advanced Solid Tumor Malignancies or Lymphomas

CompletedNCT03311412

Symphogen A/SLymphoma, Metastatic Cancer, Solid Tumor

Start: 2017-11-20End: 2022-03-23Updated: 2023-05-30

Sym022 (Anti-LAG-3) in Patients With Advanced Solid Tumor Malignancies or Lymphomas

CompletedNCT03489369

Symphogen A/SLymphoma, Metastatic Cancer, Solid Tumor

Start: 2018-05-08End: 2020-01-06Updated: 2021-02-18

Sym021 in Combination With Either Sym022 or Sym023 or Sym023 and Irinotecan in Patients With Recurrent Advanced Selected Solid Tumor Malignancies

CompletedNCT04641871

Symphogen A/SMetastatic Cancer, Solid Tumor

Start: 2020-10-12End: 2024-06-03Updated: 2024-06-26

Related Papers

Phase Ib multicenter study of anti-TIM-3 (S095018/Sym023) in combination with anti-PD-1 (Sym021) in patients with advanced/metastatic recurrent biliary tract cancer.

2026-03-13

Abstract B029: Forging strong bidirectional preclinical and translational research for optimized drug development of Sym023 (S095018), a novel anti-TIM3 antibody

Cancer Immunology Research2025-02-23

Abstract CT133: A phase 1b multicenter study of anti-TIM3 (S095018/Sym023) in combination with anti-PD1 (Sym021) in patients with advanced/metastatic recurrent biliary tract cancer

Cancer Research2024-04-052 citations

Predicting Toxicity and Response to Pembrolizumab Through Germline Genomic HLA Class 1 Analysis

JNCI Cancer Spectrum2020-12-0720 citations