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Surgical Aortic Valve Replacement (SAVR)

DEVICE4 trials

Sponsors

Medtronic Cardiovascular, Cedars-Sinai Medical Center

Conditions

Aortic Valve StenosisBicuspid Aortic ValveSevere Aortic Stenosis

Unknown Phase

Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Stenosis in High Risk and Very High Risk Subjects Who Need Aortic Valve Replacement
CompletedNCT01240902
Medtronic CardiovascularSevere Aortic Stenosis
Start: 2010-12-10End: 2019-05-15Updated: 2022-10-25
Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI).
Active, not recruitingNCT01586910
Medtronic CardiovascularSevere Aortic Stenosis
Start: 2012-04-01End: 2026-11-01Updated: 2026-06-24
Medtronic Evolut Transcatheter Aortic Valve Replacement in Low Risk Patients
Active, not recruitingNCT02701283
Medtronic CardiovascularAortic Valve Stenosis
Start: 2016-03-01End: 2029-06-01Updated: 2026-05-07
Bicuspid Aortic Valve Replacement: Evaluation of Transcatheter Versus Surgery-Pilot Trial
RecruitingNCT06817148
Cedars-Sinai Medical CenterAortic Valve Stenosis, Bicuspid Aortic Valve
Start: 2025-01-31End: 2037-02-01Target: 250Updated: 2025-02-10

Related Papers

Six-Year Outcomes After Transcatheter vs Surgical Aortic Valve Replacement in Low-Risk Patients With Aortic Stenosis.
2026-02-16
Five-year Outcomes of Transcatheter Aortic Valve Replacement Versus Surgery in Low-risk Aortic Stenosis: Insights from the Evolut Low Risk Trial.
2025-11-24
5-Year Outcomes After Transcatheter or Surgical Aortic Valve Replacement in Low-Risk Patients With Aortic Stenosis.
2025-03-3035 citations
Impact of Transcatheter or Surgical Aortic Valve Performance on 5-Year Outcomes in Patients at ≥ Intermediate Risk.
2025-03-092 citations
Use of Claims to Assess Outcomes and Treatment Effects in the Evolut Low Risk Trial
Circulation Cardiovascular Interventions2025-01-011 citations
Three-Year Outcomes Following TAVR in Younger (<75 Years) Low-Surgical-Risk Severe Aortic Stenosis Patients
Circulation Cardiovascular Interventions2024-10-186 citations
Examining the typical hemodynamic performance of nearly 3000 modern surgical aortic bioprostheses
European Journal of Cardio-Thoracic Surgery2024-05-012 citations
Quality of Life 5 Years Following Transfemoral TAVR or SAVR in Intermediate Risk Patients
JACC: Cardiovascular Interventions2024-04-0111 citations
EVOLUT Low-Risk Trial data: "We see what we want to see!"
2024-01-03
Feasibility of Coronary Access Following Redo-TAVR for Evolut Failure: A Computed Tomography Simulation Study
Circulation Cardiovascular Interventions2023-11-0125 citations
Feasibility of redo-TAVI in self-expanding Evolut valves: a CT analysis from the Evolut Low Risk Trial substudy
EuroIntervention2023-07-0138 citations
3-Year Outcomes After Transcatheter or Surgical Aortic Valve Replacement in Low-Risk Patients With Aortic Stenosis
Journal of the American College of Cardiology2023-03-05165 citations
Structural Valve Deterioration After Self-Expanding Transcatheter or Surgical Aortic Valve Implantation in Patients at Intermediate or High Risk
JAMA Cardiology2022-12-14105 citations
Functional Status After Transcatheter and Surgical Aortic Valve Replacement: 2-Year Analysis From the SURTAVI Trial.
2022-04-0110 citations
Mechanisms of Death in Low-Risk Patients After Transcatheter or Surgical Aortic Valve Replacement.
2022-03-292 citations
2-Year Outcomes After Transcatheter Versus Surgical Aortic Valve Replacement in Low-Risk Patients.
2022-03-0167 citations
Incidence and Outcomes of Infective Endocarditis After Transcatheter or Surgical Aortic Valve Replacement
Journal of the American Heart Association2021-09-2834 citations
Five-Year Clinical and Quality of Life Outcomes From the CoreValve US Pivotal Extreme Risk Trial
Circulation Cardiovascular Interventions2021-06-0123 citations
The Impact of Transfusions on Mortality After Transcatheter or Surgical Aortic Valve Replacement.
2020-11-171 citations
Clinical outcomes of TAVI or SAVR in men and women with aortic stenosis at intermediate operative risk: a post hoc analysis of the randomised SURTAVI trial
EuroIntervention2020-11-0134 citations

37 more papers not shown